P43731
Gene name |
ung (HI_0018) |
Protein name |
Uracil-DNA glycosylase |
Names |
UDG |
Species |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
KEGG Pathway |
hin:HI_0018 |
EC number |
3.2.2.27: Hydrolyzing N-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P43731
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P43731-F1 | Predicted | AlphaFoldDB |
No variants for P43731
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P43731 | |||||
No associated diseases with P43731
No regional properties for P43731
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P43731 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.2.27 | Hydrolyzing N-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| uracil DNA N-glycosylase activity | Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| base-excision repair, AP site formation via deaminated base removal | A base-excision repair, AP site formation process occurring via excision of a deaminated base. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKNWTDVIGT | EKAQPYFQHT | LQQVHLARAS | GKTIYPPQED | VFNAFKYTAF | EDVKVVILGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DPYHGPNQAH | GLAFSVKPEV | AIPPSLLNIY | KELTQDISGF | QMPSNGYLVK | WAEQGVLLLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TVLTVERGMA | HSHANLGWER | FTDKVIAVLN | EHREKLVFLL | WGSHAQKKGQ | MIDRTRHLVL |
| 190 | 200 | 210 | |||
| TAPHPSPLSA | HRGFFGCRHF | SKTNSYLESH | GIKPIDWQI |