Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P43604

Entry ID Method Resolution Chain Position Source
AF-P43604-F1 Predicted AlphaFoldDB

9 variants for P43604

Variant ID(s) Position Change Description Diseaes Association Provenance
s06-206203 15 V>I No SGRP
s06-206155 31 P>T No SGRP
s06-206085 54 P>L No SGRP
s06-206047 67 L>F No SGRP
s06-205999 83 I>V No SGRP
s06-205927 107 G>S No SGRP
s06-205920 109 S>L No SGRP
s06-205781 155 N>K No SGRP
s06-205780 156 I>V No SGRP

No associated diseases with P43604

No regional properties for P43604

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P43604

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
endoplasmic reticulum unfolded protein response The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPYAVAITV ALLIVTVSAL QVNNSCVAFP PSNLRGKNGD GTNEQYATAL LSIPWNGPPE
70 80 90 100 110 120
SLRDINLIEL EPQVALYLLE NYINHYYNTT RDNKCPNNHY LMGGQLGSSS DNRSLNDPQT
130 140 150 160
MLWPEKKEDE KNCQETFKGA CSCTKRFCKG YFSVNIFGIN LNISYSSGK