P43466

PR
Gene name
rafP
Protein name
Raffinose carrier protein
Names
Raffinose permease
Species
Pediococcus pentosaceus
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

125-269 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P43466

Entry ID Method Resolution Chain Position Source
AF-P43466-F1 Predicted AlphaFoldDB

No variants for P43466

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P43466

No associated diseases with P43466

3 regional properties for P43466

Type Name Position InterPro Accession
domain Phosphotransferase system, sugar-specific permease EIIA type 1 491 - 614 IPR001127
domain Sodium:galactoside symporter 13 - 467 IPR001927
conserved_site Sodium:galactoside symporter, conserved site 73 - 98 IPR018043

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

2 GO annotations of biological process

Name Definition
phosphoenolpyruvate-dependent sugar phosphotransferase system The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQEEHNYKWV GGRLIYGFGA KGNDAFYSIL SGYLIIFITS HLFDTGNKAL DNRMVSLVTL
70 80 90 100 110 120
IIMVLRIVEL FIDPFIGNAI DRTKNSPGHF RPWVVVGGTV SSIILLLLFT NLGGLYAKNA
130 140 150 160 170 180
MIYLVVFAIL YITMDIFYSF KDVGFWSMLP SLTTDSRERE KTATFARLGS TIGGGLVGVL
190 200 210 220 230 240
VMPAVIFFSA KATSTGDNRG WFIFALIICL IALISAWGVG LGTREVDSDI RKNKQDTVGV
250 260 270 280 290 300
MEIFKALAKN DQLLWAALAY LFYGVGINIL GSLEVYYFTY IMGKPKSFSI LSIINIFLGL
310 320 330 340 350 360
IATSLFPVLS KKFSRKGVFA GCLVFMLGGI AIFTIAGSNL WLVLLAATMF GFPQQMVFLV
370 380 390 400 410 420
VLMVITDSVE YGQLKLGHRD ESLALSVRPL IDKFGGAISN GVVGQIAIIS GMTTGATASS
430 440 450 460 470 480
ITAAGQLHFK LTMFAFPALM LLIAIGIFSK QIFLTEEKHA EIVAELERTW RTKFDNTTDQ
490 500 510 520 530 540
VAEKVVTSLD LATPIAGQVI PLAQVNDPTF AAGTLGDGFA IKPSDGRILA PFDATVRQVF
550 560 570 580 590 600
TTRHAVGLVG DNGIVLLIHI GLGTVKLRGT GFISYVEEGQ HVQQGDELLE FWDPTIKQAG
610 620 630 640
LDDTVIMTVT NSTEFTMMDW LVKPGQAVKA TDNILQLHTK A