AiPD: Autoinhibited Protein Database

P42857

Gene name	NSG1
Protein name	Neuronal vesicle trafficking-associated protein 1
Names	Neuron-enriched endosomal protein of 21 kDa, Neuron-specific protein family member 1
Species	Homo sapiens (Human)
KEGG Pathway	hsa:27065
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

16-89 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

16-89 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for P42857

Entry ID	Method	Resolution	Chain	Position	Source
AF-P42857-F1	Predicted				AlphaFoldDB

172 variants for P42857

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA91613133 rs917617293	3	K>T		No	ClinGen Ensembl
CA356131825 rs758630361	4	L>S		No	ClinGen ExAC TOPMed gnomAD
CA2832242 rs758630361	4	L>W		No	ClinGen ExAC TOPMed gnomAD
CA2832243 rs368998301	9	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1335906073 CA356131863	9	A>V		No	ClinGen gnomAD
rs747363726 CA2832244 COSM3365643	10	E>D	kidney [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1001392519 CA91613145	11	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA2832245 rs757679807	11	K>R		No	ClinGen ExAC gnomAD
CA356131873 rs757679807	11	K>T		No	ClinGen ExAC gnomAD
rs1194634219 CA356131887	13	T>I		No	ClinGen gnomAD
rs781537723 CA2832246	14	K>*		No	ClinGen ExAC gnomAD
rs746444497 CA2832247	14	K>M		No	ClinGen ExAC TOPMed gnomAD
rs768216770 CA2832248	16	P>L		No	ClinGen ExAC gnomAD
rs1432490502 CA356131926	20	D>N		No	ClinGen TOPMed
CA356131934 rs1393641138	21	G>S		No	ClinGen TOPMed
CA2832251 rs771656209	23	D>H		No	ClinGen ExAC gnomAD
TCGA novel	23	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772961206 CA2832252	24	T>I		No	ClinGen ExAC gnomAD
rs772961206 CA2832253	24	T>S		No	ClinGen ExAC gnomAD
rs1429595336 CA356131960	25	I>V		No	ClinGen TOPMed
rs776424672 CA2832255	26	P>L		No	ClinGen ExAC gnomAD
rs142822048 CA2832254	26	P>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2832258 rs752794888	27	L>R		No	ClinGen ExAC gnomAD
CA2832257 rs538259777	27	L>V		No	ClinGen ExAC TOPMed gnomAD
CA356131980 rs758577131 CA2832259	28	M>I		No	ClinGen ExAC TOPMed gnomAD
rs1233012738 CA356131977	28	M>T		No	ClinGen TOPMed gnomAD
rs764190024 CA2832260 COSM178936	29	T>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA2832262 rs757558728	30	P>A		No	ClinGen ExAC gnomAD
CA356131987 rs757558728	30	P>S		No	ClinGen ExAC gnomAD
rs1445903503 CA356131995	31	L>V		No	ClinGen gnomAD
rs746321590 CA2832264	32	D>E		No	ClinGen ExAC TOPMed gnomAD
rs563927328 CA2832263	32	D>N		No	ClinGen ExAC TOPMed gnomAD
rs756714192 CA2832265	34	N>S		No	ClinGen ExAC gnomAD
rs375219811 CA91613292	36	L>P		No	ClinGen ESP TOPMed gnomAD
rs375219811 CA356132064	36	L>R		No	ClinGen ESP TOPMed gnomAD
rs778529496 CA2832266	37	Q>*		No	ClinGen ExAC gnomAD
rs747634029 CA2832267	37	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs1399001571 CA356132083	38	F>L		No	ClinGen gnomAD
rs997806870 CA91613316	40	P>S		No	ClinGen gnomAD
CA356132129 rs1378713826	41	P>L		No	ClinGen gnomAD
rs201187038 CA91613317	42	D>A		No	ClinGen TOPMed gnomAD
CA2832268 rs771666530	43	K>N		No	ClinGen ExAC gnomAD
TCGA novel	43	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780922694 CA2832292	44	V>M		No	ClinGen ExAC gnomAD
CA356132215 rs745630280	45	V>F		No	ClinGen ExAC TOPMed gnomAD
CA2832293 rs745630280	45	V>I		No	ClinGen ExAC TOPMed gnomAD
rs149457560 CA2832295	46	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs536327777 CA2832297	50	T>N		No	ClinGen 1000Genomes ExAC gnomAD
CA2832298 rs189494221	51	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA91615116 rs189494221	51	E>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs761903599 CA2832299	53	E>D		No	ClinGen ExAC gnomAD
CA2832300 rs376464728	54	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA356132283 rs1298782205	55	D>E		No	ClinGen gnomAD
rs750726592 CA2832301	55	D>G		No	ClinGen ExAC gnomAD
CA2832302 rs761111231	56	R>C		No	ClinGen ExAC TOPMed gnomAD
rs766912597 CA2832303	56	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA2832304 rs766912597	56	R>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	56	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755518801 CA2832305	57	K>E		No	ClinGen ExAC TOPMed gnomAD
rs979112169 CA91615133	57	K>R		No	ClinGen TOPMed gnomAD
CA356132297 rs1215535939	58	K>R		No	ClinGen gnomAD
CA2832307 rs368860480	59	G>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs777095341 CA2832306	59	G>R		No	ClinGen ExAC gnomAD
rs1189497294 CA356132318	61	A>V		No	ClinGen gnomAD
rs756755886 CA2832308	62	R>C		No	ClinGen ExAC TOPMed gnomAD
rs1429276062 CA356132321	62	R>H		No	ClinGen TOPMed gnomAD
CA91615143 rs1050665	65	Q>K		No	ClinGen Ensembl
CA356132347 rs1422006747	66	I>S		No	ClinGen gnomAD
TCGA novel	68	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765800071 CA2832311	71	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs755840500 CA2832312	74	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs749132747 CA2832314	75	E>D		No	ClinGen ExAC gnomAD
CA356132407 rs1203406765	75	E>G		No	ClinGen TOPMed
TCGA novel	76	G>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2832315 rs376090767	76	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs774197830 CA2832316	76	G>V		No	ClinGen ExAC gnomAD
rs1293112575 CA356132415	77	V>L		No	ClinGen TOPMed
CA356132426 rs1458333388	79	E>K		No	ClinGen gnomAD
TCGA novel	79	E>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1234859500 CA356132434	80	R>G		No	ClinGen gnomAD
CA356134274 rs776060863	85	V>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA2832345 rs776060863	85	V>G		No	ClinGen ExAC gnomAD
rs935161247 CA356134269	85	V>L		No	ClinGen TOPMed gnomAD
rs935161247 CA91622031	85	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1560146558 CA356134298	88	L>F		No	ClinGen Ensembl
rs199877139 CA2832347	90	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA356134326 rs1373905817	90	A>V		No	ClinGen gnomAD
rs202151137 CA91622044	95	T>S		No	ClinGen 1000Genomes TOPMed
rs939101251 CA91622052	97	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA2832351 rs753488927 COSM3380934	98	V>I	pancreas [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1207000008 CA356134424	99	F>C		No	ClinGen gnomAD
TCGA novel	101	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA91622067 rs375393695	106	Y>*		No	ClinGen Ensembl
CA2832353 rs367556298	107	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA356134555 rs1235892846	108	Y>F		No	ClinGen gnomAD
CA356134540 rs1419264747	108	Y>H		No	ClinGen TOPMed
rs1455179900 CA356134581	109	D>V		No	ClinGen gnomAD
CA2832355 rs758435608	110	R>C		No	ClinGen ExAC gnomAD
rs777962457 CA2832356	110	R>H		No	ClinGen ExAC TOPMed gnomAD
rs777962457 CA2832357	110	R>L		No	ClinGen ExAC TOPMed gnomAD
CA356134604 rs777962457	110	R>P		No	ClinGen ExAC TOPMed gnomAD
rs781465005 CA2832359	111	A>T		No	ClinGen ExAC gnomAD
rs62287955 CA91622087	113	P>S		No	ClinGen TOPMed
CA356134633 rs62287955	113	P>T		No	ClinGen TOPMed
COSM481291 rs770129715 CA2832361	114	D>N	kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs770129715 CA356134651	114	D>Y		No	ClinGen ExAC TOPMed gnomAD
rs376799919 CA2832364	116	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA356134730 rs1216691848	117	V>A		No	ClinGen gnomAD
CA2832365 COSM178939 rs368098188	117	V>I	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA2832410 rs761707011	120	N>D		No	ClinGen ExAC gnomAD
CA2832411 rs767334264	121	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1316604323 CA356133273	122	Q>E		No	ClinGen gnomAD
rs142424223 CA2832412	124	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs552690442 CA91590094	125	P>L		No	ClinGen 1000Genomes
CA2832413 rs370655501	126	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs1171117599 CA356133310	127	G>D		No	ClinGen gnomAD
rs753998040 CA2832415	129	E>D		No	ClinGen ExAC gnomAD
rs766449226 CA2832414	129	E>Q		No	ClinGen ExAC gnomAD
rs1331233492 CA356133328	130	S>N		No	ClinGen gnomAD
CA2832417 rs377273535	132	Y>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs755211489 CA2832416	132	Y>C		No	ClinGen ExAC gnomAD
rs758849842 COSM2848203 CA2832419	133	A>T	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA2832420 rs199605150	133	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA2832422 rs769363422	134	E>G		No	ClinGen ExAC gnomAD
rs775154077 CA2832423	136	D>A		No	ClinGen ExAC TOPMed gnomAD
CA356133371 rs1199247783	136	D>E		No	ClinGen gnomAD
rs151272786 CA2832424	137	S>F		No	ClinGen ESP ExAC gnomAD
rs768392670 CA2832425	139	A>T		No	ClinGen ExAC gnomAD
rs1215573369 CA356133390	139	A>V		No	ClinGen gnomAD
CA2832427 rs139279868	140	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs774194888 CA2832426	140	R>W		No	ClinGen ExAC gnomAD
CA2832429 rs767411596	141	E>A		No	ClinGen ExAC TOPMed gnomAD
CA2832428 rs767411596	141	E>G		No	ClinGen ExAC TOPMed gnomAD
CA91590199 rs368639342	145	T>R		No	ClinGen ESP gnomAD
rs766394146 CA2832432	146	V>D		No	ClinGen ExAC gnomAD
CA91590213 rs370574850	147	I>V		No	ClinGen Ensembl
TCGA novel	148	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2832433 rs756592403	148	N>S		No	ClinGen ExAC gnomAD
rs759656418 CA2832434	149	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA2832435 rs765425937	150	Y>S		No	ClinGen ExAC gnomAD
CA2832437 rs758687002	151	N>T		No	ClinGen ExAC gnomAD
CA2832438 rs778206077	152	L>Q		No	ClinGen ExAC gnomAD
rs935852509 CA91590259	156	S>G		No	ClinGen gnomAD
rs935852509 CA356133494	156	S>R		No	ClinGen gnomAD
rs1266166508 CA356133505	157	I>T		No	ClinGen gnomAD
CA356133502 rs1215482313	157	I>V		No	ClinGen gnomAD
CA356133509 rs1187079400	158	T>A		No	ClinGen Ensembl
rs200509666 CA2832440	158	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs748784768 CA2832442	159	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA2832443 rs768337643	159	R>H		No	ClinGen ExAC TOPMed
rs778424353 CA2832444	160	S>F		No	ClinGen ExAC gnomAD
CA2832446 rs771703231	161	V>I		No	ClinGen ExAC TOPMed gnomAD
CA356133522 rs771703231 CA2832447	161	V>L		No	ClinGen ExAC TOPMed gnomAD
rs371964701 CA2832448	162	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	163	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356133533 rs1157375287	163	P>S		No	ClinGen gnomAD
CA356133559 rs1456942832	166	S>L		No	ClinGen gnomAD
CA356133563 rs1291451223	167	V>F		No	ClinGen gnomAD
CA2832450 rs776603475	170	E>G		No	ClinGen ExAC TOPMed gnomAD
rs1577299876 CA356133586	171	E>K		No	ClinGen Ensembl
rs1416644375 CA356133602	173	L>V		No	ClinGen TOPMed gnomAD
rs898277275 CA91590329	174	S>Y		No	ClinGen Ensembl
rs764316745 CA2832455	175	E>K		No	ClinGen ExAC TOPMed gnomAD
rs751985740 CA2832456	176	Q>H		No	ClinGen ExAC gnomAD
CA2832457 rs757744145	177	E>G		No	ClinGen ExAC gnomAD
CA356133625 rs1262731210	177	E>Q		No	ClinGen TOPMed gnomAD
CA91590347 rs1050434947	178	T>A		No	ClinGen TOPMed
CA2832459 COSM1055610 rs751035703	180	A>V	endometrium [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA2832461 rs778496206	182	E>G		No	ClinGen ExAC gnomAD
rs754469690 CA2832460	182	E>K		No	ClinGen ExAC gnomAD
CA356133677 rs1256024403	185	A>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA356133676 rs1256024403	185	A>T		No	ClinGen gnomAD

No associated diseases with P42857

No regional properties for P42857

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for P42857

Functions

		Description
EC Number
Subcellular Localization	Membrane ; Single-pass type II membrane protein Golgi apparatus, trans-Golgi network membrane Endosome membrane Cell projection, dendrite Early endosome membrane Late endosome membrane Lysosome lumen Recycling endosome membrane Cytoplasmic vesicle membrane Golgi apparatus, Golgi stack membrane Endosome, multivesicular body membrane Endoplasmic reticulum membrane	Endocytosed from the cell surface, thus enters into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity) Endoplasmic reticulum targeting is essential for apoptosis (PubMed:20599942) Found in both stationary and motile endosomes A previous study supports a type I membrane protein topology (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

19 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
dendrite	A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
early endosome membrane	The lipid bilayer surrounding an early endosome.
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
endosome	A vacuole to which materials ingested by endocytosis are delivered.
glutamatergic synapse	A synapse that uses glutamate as a neurotransmitter.
Golgi cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
late endosome	A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
lateral plasma membrane	The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
lysosomal lumen	The volume enclosed within the lysosomal membrane.
multivesicular body membrane	The lipid bilayer surrounding a multivesicular body.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
postsynaptic endosome	An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.
postsynaptic membrane	A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
recycling endosome membrane	The lipid bilayer surrounding a recycling endosome.
somatodendritic compartment	The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.
trans-Golgi network membrane	The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.

2 GO annotations of molecular function

Name	Definition
clathrin light chain binding	Binding to a clathrin light chain.
signaling receptor binding	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

13 GO annotations of biological process

Name	Definition
amyloid precursor protein metabolic process	The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
clathrin coat assembly	The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
endosomal transport	The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
neurotransmitter receptor cycle	The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).
neurotransmitter receptor transport, endosome to postsynaptic membrane	The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
positive regulation of receptor recycling	Any process that activates or increases the frequency, rate or extent of receptor recycling.
postsynaptic neurotransmitter receptor cycle	The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
receptor recycling	The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.
regulation of long-term synaptic potentiation	Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.
spontaneous synaptic transmission	The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
vesicle-mediated transport in synapse	Any vesicle-mediated transport that occurs in a synapse.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MVKLGNNFAE	KGTKQPLLED	GFDTIPLMTP	LDVNQLQFPP	PDKVVVKTKT	EYEPDRKKGK
70	80	90	100	110	120
ARPPQIAEFT	VSITEGVTER	FKVSVLVLFA	LAFLTCVVFL	VVYKVYKYDR	ACPDGFVLKN
130	140	150	160	170	180
TQCIPEGLES	YYAEQDSSAR	EKFYTVINHY	NLAKQSITRS	VSPWMSVLSE	EKLSEQETEA

AEKSA