P42321

PR
Gene name
katA
Protein name
Catalase
Names
Species
Proteus mirabilis
KEGG Pathway
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

345-435 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

10 structures for P42321

Entry ID Method Resolution Chain Position Source
1E93 X-ray 200 A A 1-484 PDB
1H6N X-ray 211 A A 1-484 PDB
1H7K X-ray 240 A A 2-484 PDB
1M85 X-ray 200 A A 1-484 PDB
1MQF X-ray 250 A A 1-484 PDB
1NM0 X-ray 230 A A 1-484 PDB
2CAG X-ray 270 A A 1-484 PDB
2CAH X-ray 270 A A 1-484 PDB
3HB6 X-ray 230 A A 1-484 PDB
AF-P42321-F1 Predicted AlphaFoldDB

No variants for P42321

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P42321

No associated diseases with P42321

5 regional properties for P42321

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 161 - 500 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 68 - 145 IPR004365
domain Aminoacyl-tRNA synthetase, class II 186 - 502 IPR006195
domain Lysyl-tRNA synthetase, class II, C-terminal 176 - 502 IPR018149
domain Lysine-tRNA ligase, class II, N-terminal 68 - 173 IPR044136

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKKKLTTAA GAPVVDNNNV ITAGPRGPML LQDVWFLEKL AHFDREVIPE RRMHAKGSGA
70 80 90 100 110 120
FGTFTVTHDI TKYTRAKIFS EVGKKTEMFA RFSTVAGERG AADAERDIRG FALKFYTEEG
130 140 150 160 170 180
NWDMVGNNTP VFYLRDPLKF PDLNHIVKRD PRTNMRNMAY KWDFFSHLPE SLHQLTIDMS
190 200 210 220 230 240
DRGLPLSYRF VHGFGSHTYS FINKDNERFW VKFHFRCQQG IKNLMDDEAE ALVGKDRESS
250 260 270 280 290 300
QRDLFEAIER GDYPRWKLQI QIMPEKEAST VPYNPFDLTK VWPHADYPLM DVGYFELNRN
310 320 330 340 350 360
PDNYFSDVEQ AAFSPANIVP GISFSPDKML QGRLFSYGDA HRYRLGVNHH QIPVNAPKCP
370 380 390 400 410 420
FHNYHRDGAM RVDGNSGNGI TYEPNSGGVF QEQPDFKEPP LSIEGAADHW NHREDEDYFS
430 440 450 460 470 480
QPRALYELLS DDEHQRMFAR IAGELSQASK ETQQRQIDLF TKVHPEYGAG VEKAIKVLEG
KDAK