P42234

PR
Gene name
katE (katB, BSU39050, N15D)
Protein name
Catalase-2
Names
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU39050
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P42234

Entry ID Method Resolution Chain Position Source
AF-P42234-F1 Predicted AlphaFoldDB

No variants for P42234

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P42234

No associated diseases with P42234

5 regional properties for P42234

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 361 - 369 IPR002226
domain Catalase immune-responsive domain 446 - 510 IPR010582
domain Catalase core domain 31 - 419 IPR011614
active_site Catalase active site 67 - 83 IPR024708
domain Large catalase, C-terminal domain 541 - 684 IPR041399

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

3 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
sporulation resulting in formation of a cellular spore The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDDQNKRVN EHSKDEQLEQ YRTDNSGKKM TTNQGLRVSE DEHSLKAGVR GPTLMEDFHF
70 80 90 100 110 120
REKMTHFDHE RIPERVVHAR GFGVHGFFQV YEPMTEYTRA KFLQDPSVKT PVFVRFSTVA
130 140 150 160 170 180
GSKGSADTVR DARGFATKFY TEEGNYDLVG NNIPVFFIQD AIKFPDLVHA FKPEPHNEMP
190 200 210 220 230 240
QAATAHDTFW DFVANNPESA HMVMWTMSDR GIPRSYRMME GFGVHTFRFV NEQGKARFVK
250 260 270 280 290 300
FHWKPVLGVH SLVWDEAQKI AGKDPDFHRR DLWETIENGG KVEYELGVQM IDEEDEFKFD
310 320 330 340 350 360
FDILDPTKLW PEELVPVKII GKMTLNRNQD NVFAETEQVA FHPGNVVPGI DFTNDPLLQG
370 380 390 400 410 420
RLFSYTDTQL IRLGGPNFHE IPINRPVCPF HNNQYDGYHR MTINKGPVAY HKNSLQNNDP
430 440 450 460 470 480
SPATAEEGGY VHYQEKVEGK KIRQRSDSFN DYYSQAKLFW NSMSPVEKQH IISAFCFEVG
490 500 510 520 530 540
KVKSKDVQRQ VVDVFSNVDA DLAEEIAKGV GVAAPAKRKA SKEILTSPAL SQARTVKTAS
550 560 570 580 590 600
TRKVAVLAGN GFHEKELQTV LEALKQEGIT VDIISQNLGY MTSGSGQQLE ASGTFLTVDS
610 620 630 640 650 660
VLYDAVYAAG GLELKDNKQA MAFIREAYNH YKAIGAANEG IDLLQSSVGT TEGLGIVTAK
670 680
DEPDYTAFSK AFIDAVAAHR HWDRRI