P41592

PR
Gene name
Protein name
Red-sensitive opsin
Names
Red cone photoreceptor pigment
Species
Anolis carolinensis (Green anole) (American chameleon)
KEGG Pathway
acs:100564371
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

316-369 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P41592

Entry ID Method Resolution Chain Position Source
AF-P41592-F1 Predicted AlphaFoldDB

No variants for P41592

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P41592

No associated diseases with P41592

2 regional properties for P41592

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 73 - 325 IPR017452
binding_site Visual pigments (opsins) retinal binding site 309 - 325 IPR027430

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cell body The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
photoreceptor inner segment membrane The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
photoreceptor outer segment The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
vesicle Any small, fluid-filled, spherical organelle enclosed by membrane.

3 GO annotations of molecular function

Name Definition
chloride ion binding Binding to a chloride ion (Cl-).
G protein-coupled photoreceptor activity Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
protein homodimerization activity Binding to an identical protein to form a homodimer.

7 GO annotations of biological process

Name Definition
absorption of visible light The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
G protein-coupled receptor signaling pathway The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
light absorption The reception of a photon by a cell.
phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
protein homotrimerization The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGTVTEAWD VAVFAARRRN DEDDTTRDSL FTYTNSNNTR GPFEGPNYHI APRWVYNITS
70 80 90 100 110 120
VWMIFVVIAS IFTNGLVLVA TAKFKKLRHP LNWILVNLAI ADLGETVIAS TISVINQISG
130 140 150 160 170 180
YFILGHPMCV LEGYTVSTCG ISALWSLAVI SWERWVVVCK PFGNVKFDAK LAVAGIVFSW
190 200 210 220 230 240
VWSAVWTAPP VFGWSRYWPH GLKTSCGPDV FSGSDDPGVL SYMIVLMITC CFIPLAVILL
250 260 270 280 290 300
CYLQVWLAIR AVAAQQKESE STQKAEKEVS RMVVVMIIAY CFCWGPYTVF ACFAAANPGY
310 320 330 340 350 360
AFHPLAAALP AYFAKSATIY NPIIYVFMNR QFRNCIMQLF GKKVDDGSEL SSTSRTEVSS
VSNSSVSPA