P41127
Gene name |
RPL13B (BBC1, At3g49010, T2J13.150) |
Protein name |
60S ribosomal protein L13-1 |
Names |
Protein BBC1 homolog |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G49010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P41127
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P41127-F1 | Predicted | AlphaFoldDB |
11 variants for P41127
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_18168020_C_A | 10 | G>C | No | 1000Genomes | |
| ENSVATH14404874 | 36 | A>V | No | 1000Genomes | |
| ENSVATH12652105 | 83 | G>C | No | 1000Genomes | |
| ENSVATH06275511 | 92 | I>V | No | 1000Genomes | |
| ENSVATH02473544 | 103 | R>L | No | 1000Genomes | |
| tmp_3_18167332_T_C | 120 | T>A | No | 1000Genomes | |
| tmp_3_18167323_C_T | 123 | V>I | No | 1000Genomes | |
| ENSVATH12652062 | 157 | R>P | No | 1000Genomes | |
| tmp_3_18167123_G_T | 157 | R>S | No | 1000Genomes | |
| tmp_3_18167056_T_A | 179 | K>M | No | 1000Genomes | |
| tmp_3_18167048_G_A | 182 | L>F | No | 1000Genomes |
No associated diseases with P41127
1 regional properties for P41127
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Ribosomal protein L13e, conserved site | 69 - 83 | IPR018256 |
8 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| cytosolic ribosome | A ribosome located in the cytosol. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| plant-type cell wall | A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances. |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
| polysomal ribosome | A ribosome bound to mRNA that forms part of a polysome. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKHNNVIPNG | HFKKHWQNYV | KTWFNQPARK | TRRRIARQKK | AVKIFPRPTS | GPLRPVVHGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TLKYNMKVRT | GKGFTLEELK | AAGIPKKLAP | TIGIAVDHRR | KNRSLEGLQT | NVQRLKTYKT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLVIFPRRAR | KVKAGDSTPE | ELANATQVQG | DYLPIVREKP | TMELVKLTSE | MKSFKAFDKI |
| 190 | 200 | ||||
| RLERTNKRHA | GARAKRAAEA | EKEEKK |