Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P40990

Entry ID Method Resolution Chain Position Source
AF-P40990-F1 Predicted AlphaFoldDB

13 variants for P40990

Variant ID(s) Position Change Description Diseaes Association Provenance
s04-269075 52 S>L No SGRP
s04-269089 57 E>Q No SGRP
s04-269098 60 I>V No SGRP
s04-269323 135 Y>N No SGRP
s04-269350 144 E>K No SGRP
s04-269429 170 T>I No SGRP
s04-269478 186 N>K No SGRP
s04-269477 186 N>S No SGRP
s04-269593 225 I>V No SGRP
s04-269602 228 S>C No SGRP
s04-269670 250 L>F No SGRP
s04-269891 324 N>S No SGRP
s04-269898 326 K>N No SGRP

No associated diseases with P40990

No regional properties for P40990

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P40990

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extrinsic component of mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein insertion into mitochondrial inner membrane from matrix The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQRFVSKFVS TPPVPKKFQE IFPKKRTVNK ILFQLDTRLT YHEMYPIFLQ VSQNTNEENI
70 80 90 100 110 120
PWRKKYPYIR SSDIMQMRNV LITLRTQNKF VHKDLLAMED KLLNIAAELG NNDAISILSF
130 140 150 160 170 180
NVIHEYKKEN VKSSYEKDIE TANEFIKKLY ARNHHLTVKL IGDLFFENKT YDKAEKYYQE
190 200 210 220 230 240
FLKLENSTKL AGEVHGKLGE IQIKQVNGFL KAEKSWLSCI ELLEIERSSR WYFLLARLYM
250 260 270 280 290 300
SSEPMKAKAL LENCASIGFK ECFKTLGFLE LNYFNNYERA KEWFKTGMEI MDLECFFGFF
310 320 330 340 350
DCCVKEENFK GARDCLESVK KLGNDKDKKT MINVFLESRK DSIKLLDKAR L