Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P40560

Entry ID Method Resolution Chain Position Source
AF-P40560-F1 Predicted AlphaFoldDB

10 variants for P40560

Variant ID(s) Position Change Description Diseaes Association Provenance
s09-354343 136 A>V No SGRP
s09-354374 146 E>D No SGRP
s09-354654 240 S>G No SGRP
s09-354745 270 C>Y No SGRP
s09-354829 298 S>N No SGRP
s09-354859 308 T>R No SGRP
s09-354864 310 N>D No SGRP
s09-354903 323 V>F No SGRP
s09-354921 329 S>R No SGRP
s09-354961 342 E>A No SGRP

No associated diseases with P40560

3 regional properties for P40560

Type Name Position InterPro Accession
domain BTB/POZ domain 122 - 219 IPR000210-1
domain BTB/POZ domain 266 - 390 IPR000210-2
repeat Ankyrin repeat 8 - 70 IPR002110

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADKLMDKNF EELCYSCRTG DMDNVDRLIS TGVNVNSVDK FDNSPLFLAS LCGHEAVVKL
70 80 90 100 110 120
LLQRGAVCDR DRYEGARCIY GALTDTIRDT LLSYDISKAV DVKQPFATHI SSMYNDEGFL
130 140 150 160 170 180
KRDITFRVSN GKLFTAHKFL LCARSEILAE KMVNEWAKHE IVSLEVRPDI FDIFLKFLYL
190 200 210 220 230 240
IPILHQIEPG QYEELIELSS KFDIELLPEF LDKARHTADP TEKSRLMSDY QYKFTEVARS
250 260 270 280 290 300
QLLIFVNNCI FRSTVDLANS ERRVFSLMNC PAYPDVQLMV KNRNGAIRIY PCHLAVLSRA
310 320 330 340 350 360
EYFKVMFTNN FKEKVTYIKA KHVTGKYNSI IPQLTLPNCE FEVAEIILRY LYADNTDIPW
370 380 390 400 410 420
MYAVDVLLLA DILLEDRLKT IASTIITQSK EFIQQYNVFD VLYLSWEIGV ERLEQFAAKF
430 440 450 460 470 480
IAIHLQELYK DPEIKRAIML SSQRISLRQE TDTIELVDDI RYYLLRKYSF EPDDVELFEN
490 500 510
QDDLEYLKQV GYLEYRKDMG MLDNILADLE LDV