P40390
Gene name |
pgm |
Protein name |
Phosphoglucomutase |
Names |
PGM, Glucose phosphomutase |
Species |
Neisseria gonorrhoeae |
KEGG Pathway |
|
EC number |
5.4.2.2: Phosphotransferases (phosphomutases) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40390
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40390-F1 | Predicted | AlphaFoldDB |
No variants for P40390
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P40390 | |||||
No associated diseases with P40390
5 regional properties for P40390
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Thiolase, active site | 374 - 387 | IPR020610 |
| conserved_site | Thiolase, conserved site | 339 - 355 | IPR020613 |
| active_site | Thiolase, acyl-enzyme intermediate active site | 84 - 102 | IPR020615 |
| domain | Thiolase, N-terminal | 4 - 262 | IPR020616 |
| domain | Thiolase, C-terminal | 270 - 392 | IPR020617 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.2.2 | Phosphotransferases (phosphomutases) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| phosphoglucomutase activity | Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glucose metabolic process | The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASITRDIFK | AYDIRGIVGK | TLTDDAAYFI | GRAIAAKAAE | KGIARIALGR | DGRLSGPELM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EHIQRGLTDS | GISVLNVGMV | TTPMLYFAAV | NECGGSGVMI | TGSHNPPDYN | GFKMMLGGDT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LAGEAIQELL | AIVEKDGFVA | ADKQGSVTEK | DISGAYHDHI | VGHVKLKRPI | NIAIDAGNGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GGAFAGKLYK | GLGNEVTELF | CEVDGNFPNH | HPDPSKPENL | QDLIAALKNG | DAEIGLAFDG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DADRLGVVTK | DGNIIYPDRQ | LMLFAQDVLN | RNPGAKVIFD | VKSTRLLAPW | IKEHGGEAIM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EKTGHSFIKS | AMKKTGALVA | GEMSGHVFFK | ERWFGFDDGL | YAGARLLEIL | SASDNPSEVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DNLPQSISTP | ELNISLPEGS | NGHQVIEELA | AKAEFEGATE | IITIDGLRVE | FPDGFGLMRA |
| 430 | 440 | 450 | |||
| SNTTPILVLR | FEADTQAAIE | RIQNRFKAVI | ESNPHLIWPL |