P40173
Gene name |
fusA (fus, SCO4661, SCD840A.07) |
Protein name |
Elongation factor G 1 |
Names |
EF-G 1 |
Species |
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
KEGG Pathway |
sco:SCO4661 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40173
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40173-F1 | Predicted | AlphaFoldDB |
No variants for P40173
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P40173 | |||||
No associated diseases with P40173
9 regional properties for P40173
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Elongation factor EFG, domain V-like | 614 - 701 | IPR000640 |
| domain | Translational (tr)-type GTP-binding domain | 9 - 295 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 336 - 402 | IPR004161 |
| domain | Small GTP-binding protein domain | 11 - 185 | IPR005225 |
| domain | Translation elongation factor EFG/EF2, domain IV | 491 - 612 | IPR005517 |
| domain | Elongation factor G, domain III | 417 - 492 | IPR009022 |
| conserved_site | Tr-type G domain, conserved site | 52 - 67 | IPR031157 |
| domain | EFG, domain V | 617 - 694 | IPR035649 |
| domain | Elongation Factor G, domain II | 416 - 490 | IPR041095 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosome disassembly | The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATTSLDLAK | VRNIGIMAHI | DAGKTTTTER | ILFYTGVSYK | IGEVHDGAAT | MDWMEQEQER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GITITSAATT | CHWPLEDNDY | TINIIDTPGH | VDFTVEVERS | LRVLDGAVTV | FDGVAGVEPQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SETVWRQADR | YGVPRICFVN | KLDRTGAEFH | RCVDMISDRL | GAQPLVMQLP | IGAEADFQGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VDLVRMKALV | WSADAAKGEM | YDVVDIPATH | TEAAEEWRGK | LVEAVAENDE | EVMELFLEGQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EPTEEQLYAA | IRRVTIASGK | SSDTTVTPVF | CGTAFKNKGV | QPLLDAVVRY | LPTPLDVEAI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EGHDVKDPEV | VVKRKPSEDE | PLAALAFKIM | SDPHLGKLTF | VRVYSGRLVS | GTAVLNSVKG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKERIGKIYR | MHANKREEIE | SVGAGDIVAV | MGLKQTTTGE | TLSDDKSPVI | LESMDFPAPV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IQVAIEPKSK | GDQEKLGVAI | QRLAEEDPSF | QVHTNEETGQ | TIIGGMGELH | LEVLVDRMRR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EFKVEANVGK | PQVAYRETIR | KTVERVDYTH | KKQTGGTGQF | AKVQIAIEPI | EGGDASYEFV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NKVTGGRIPK | EYIPSVDAGA | QEAMQFGILA | GYEMTGVRVT | LIDGGYHEVD | SSELAFKIAG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SQAFKEAARK | ASPVLLEPMM | AVEVTTPEDY | MGDVIGDINS | RRGQIQAMEE | RMGARVVKGL |
| 670 | 680 | 690 | 700 | ||
| VPLSEMFGYV | GDLRSKTSGR | ASYSMQFDSY | AEVPRNVAEE | IIAKAKGE |