P40157
Gene name |
VID27 (YNL212W, N1327) |
Protein name |
Vacuolar import and degradation protein 27 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YNL212W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40157
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40157-F1 | Predicted | AlphaFoldDB |
10 variants for P40157
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s14-247568 | 36 | A>V | No | SGRP | |
| s14-247603 | 48 | V>I | No | SGRP | |
| s14-248208 | 249 | K>N | No | SGRP | |
| s14-248228 | 256 | V>A | No | SGRP | |
| s14-248237 | 259 | V>A | No | SGRP | |
| s14-248557 | 366 | D>N | No | SGRP | |
| s14-248825 | 455 | V>A | No | SGRP | |
| s14-248974 | 505 | I>V | No | SGRP | |
| s14-249223 | 588 | I>L | No | SGRP | |
| s14-249392 | 644 | N>T | No | SGRP |
No associated diseases with P40157
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNILKKFMES | GNKPELITIP | SGQFNLLRSK | NSPKAALECI | YNNATLSVRK | IGKFDYELAV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YRVEDDSEGG | TGDEAENFED | DTISVLSTQS | KKKEEEWSVE | ISDKIMFHKT | WDKQGNVALV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WENLRGDEQD | EKVQFVVAAD | VSFSDVEQFI | QTVYRCQFEV | RNKKSSLTAS | ADDLKEIEHR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| STRLFVQDDD | DELDSSSDDF | QDAKDTSFEH | EKESEILERT | PSPLKKVPEG | EYCCLVMSSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YMYDPIQEKF | ILQEPVVKVA | IIDTGKYEFW | LAIEGKDNRL | GTQVAPNINP | TFELATDAFL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FNYTLQNITL | SYMLKFKDLD | KCIQFRFAWV | KCLWMTLNKE | TWTDVPEKEK | DYILDSSSVP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LEKQFDDILH | IDDRSNEERD | KESSESENDS | EDEDDENDHS | KRIISSEAFE | EPRRATSKGN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SSLTVAFRNN | RSYVTRDNRI | GVFKTDDEDD | SLEFVAAIKN | ISNLGGKSID | PHKPMLYMED |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RNLILTDGEN | ENKLYKMDIE | RGKVIEEWST | GDKNVVQYGP | TKKFDQMTPE | QTIVGVSQKG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VFKIDPRING | KNKIAVDESK | DYVGKYNFSS | IGTTESGYIA | IGSEKGDIKL | YDRLGIRAKT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AIPSLGQAIK | FITTSADGKW | LLATCESTLL | LMDLKIKDGK | NAGNIGFLKS | FPASENVKTY |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VLKIRPEHSA | SILTYTKKPI | RFTKAYFNTG | IGQQEQTIVT | STGPYAISWS | LKGILNQDGS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NNYPYRIRRY | NADVVADNFE | FGSDKKVIVA | LKDDVSLSKV | KSFKQPSKGV | LMPSASLQDF |
| YG |