P40050
Gene name |
MRX1 |
Protein name |
MIOREX complex component 1 |
Names |
Mitochondrial organization of gene expression protein 1 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YER077C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40050
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40050-F1 | Predicted | AlphaFoldDB |
13 variants for P40050
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s05-316224 | 125 | N>D | No | SGRP | |
| s05-316218 | 127 | A>T | No | SGRP | |
| s05-316170 | 143 | F>V | No | SGRP | |
| s05-316082 | 172 | N>S | No | SGRP | |
| s05-315972 | 209 | I>F | No | SGRP | |
| s05-315853 | 248 | E>D | No | SGRP | |
| s05-315131 | 489 | T>M | No | SGRP | |
| s05-315053 | 515 | A>G | No | SGRP | |
| s05-314975 | 541 | R>K | No | SGRP | |
| s05-314943 | 552 | V>L | No | SGRP | |
| s05-314853 | 582 | F>L | No | SGRP | |
| s05-314628 | 657 | R>G | No | SGRP | |
| s05-314585 | 671 | R>H | No | SGRP |
No associated diseases with P40050
1 regional properties for P40050
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pentatricopeptide repeat | 197 - 246 | IPR002885 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGLKITKGQL | RTKDLNQSSS | KSSQSSRIGV | DTCIFTRMLP | RINTAINLTE | HLLRRSFHSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TNLQKTQVKE | RLHELERHGF | ILNKTSKQLE | RINSKKRRQL | KKLQKTAYPK | DQAFHILRKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HKINNEALAD | TKLGPTSQSD | LKFLSLTKDK | RLFYTILGVN | GEQLRDSKLI | ANDVQKFLKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GQLEKAVFLA | RLAKKKGVVG | MNLIMKYYIE | VVQSQQSAVD | IFNWRKKWGV | PIDQHSITIL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FNGLSKQENL | VSKKYGELVL | KTIDSLCDKN | ELTEIEYNTA | LAALINCTDE | TLVFKLLNKK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CPGLKKDSIT | YTLMIRSCTR | IADEKRFMVV | LNDLMNKIPD | YCVDSKLLFE | YCEVICSQKS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PKIEKQGMGL | WALCEYFQFD | KTIFKKYLTQ | SDFPTLVPLS | HWNINKPFPL | NKHVVGLFMN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YCLKNKEYDL | AMEIFKTLEA | QNNQMLDQSI | YHKYMETVIT | TRPITCGDEC | LDIYERVASS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AQISITRRTL | ILVYNAFQRQ | SLKAVINKDA | SNAEATLHKI | RGFIDSVEAT | YSSKLNGKVY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RFNSWKFLFP | IVKNLNMNDK | VSTVELKSIL | DEYLKSLLNG | EFGKEFKASI | EDKRFVTLEG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IRLVKVLTER | IKLPSLDSEE | IASLKGTERK | KFLARRHLLR | LKQILLEDLA | DIEGNSRRKG |
| 670 | 680 | ||||
| DSENTSTSEE | RIMEDLAELI | LETSYDKF |