P39863

PR
Gene name
NIA
Protein name
Nitrate reductase [NADPH]
Names
NR
Species
Fusarium oxysporum (Fusarium vascular wilt)
KEGG Pathway
EC number
1.7.1.3: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P39863

Entry ID Method Resolution Chain Position Source
AF-P39863-F1 Predicted AlphaFoldDB

No variants for P39863

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P39863

No associated diseases with P39863

11 regional properties for P39863

Type Name Position InterPro Accession
domain Oxidoreductase, molybdopterin-binding domain 131 - 307 IPR000572
domain Cytochrome b5-like heme/steroid binding domain 546 - 621 IPR001199
domain Oxidoreductase FAD/NAD(P)-binding 778 - 889 IPR001433
domain Flavoprotein pyridine nucleotide cytochrome reductase 777 - 796 IPR001709-1
domain Flavoprotein pyridine nucleotide cytochrome reductase 815 - 826 IPR001709-2
domain Flavoprotein pyridine nucleotide cytochrome reductase 875 - 883 IPR001709-3
domain Moybdenum cofactor oxidoreductase, dimerisation 335 - 482 IPR005066
domain Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain 653 - 758 IPR008333
domain FAD-binding domain, ferredoxin reductase-type 648 - 759 IPR017927
binding_site Cytochrome b5, heme-binding site 577 - 584 IPR018506
binding_site Oxidoreductase, molybdopterin binding site 151 - 186 IPR022407

Functions

Description
EC Number 1.7.1.3 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
molybdenum ion binding Binding to a molybdenum ion (Mo).
molybdopterin cofactor binding Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
nitrate reductase (NADPH) activity Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.

2 GO annotations of biological process

Name Definition
nitrate assimilation The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
METSTTTTLL QQERIPENSE PISTHIHTHS LPPTPPGTAK PSRIGSFHDL QELSSVESPR
70 80 90 100 110 120
LDHIKPYPLP PKFSPKSVLK EDLKTPDNFV ERDPRLIRLT GVHPFNVEAP LSDLYDEGFL
130 140 150 160 170 180
TSENLHYVRN HGHVPRCEDD DILDWEFEIS GLVENPIKMN VRDLINDYQQ LTYPVTFVCA
190 200 210 220 230 240
GNRRKEQNIV RKTKGFSWGP AGLSTALWTG VAIGDLLSAA KPKRGARYVC FEGADKLPNG
250 260 270 280 290 300
YYGTSIKLNW CMDPNRGVMV AHKMNGNPLP PDHGKPVRIV IPGQIGGRSI KWLKKITITQ
310 320 330 340 350 360
EPSDNWYHIY DNRVLPTMIS PEESANLPEV WKDEKYAIYD LSTNSAICYP AHEEKVPFTD
370 380 390 400 410 420
APASYKVRGY AYSGGGRRIT RVEVTLDKGK SWRLANIRYP EDDYRNAPEG DTLYGGRVDM
430 440 450 460 470 480
WWRETSFCWC FWDLDIPLDE LKSADDIMMR AMDESMNVQP RDMYWSVLGM MNNPWFRIVI
490 500 510 520 530 540
HKEDHALRFE HPTHATLKIK GWMERVKEAG GDLTNGYWGE KAPGEVQEVV VKEPEKQICM
550 560 570 580 590 600
TNPQINRKIT IEELKAHSGE EEPWFVVKGE VYDGTPYLSG HPGGAASIFG AAGQDATEEF
610 620 630 640 650 660
MAIHSENAKA MLPTYHIGTL DEESRAILSG DATKTNDDAD REVFLQAKTW SKAILDKKTS
670 680 690 700 710 720
ISPDTKIFSF KLNHEAQKIG LPTGQHLMMR LRDPATREAI IRSYTPYSDG SDCGRLDILI
730 740 750 760 770 780
KIYYDTPQRK GGVMTQALDA LPIGHWVDFK GPTGKFVYHG NGLCTINEKE RRVRRFIMVC
790 800 810 820 830 840
GGSGITPIRQ VLRAVIDNPK DTTPCLVFNG NRSVNDILCM EELEELEAAN PSRCRVVNAL
850 860 870 880 890 900
SNPPPEWNGL KGFVNQALVP EYMDLPKASG EGDELLLVCG PPPMVKAVEA SFLGMGFKSD
DFVFF