P39664
Gene name |
sphS (Synpcc7942_1011) |
Protein name |
Sensor protein SphS |
Names |
|
Species |
Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans R2) |
KEGG Pathway |
syf:Synpcc7942_1011 |
EC number |
2.7.13.3: Protein-histidine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P39664
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P39664-F1 | Predicted | AlphaFoldDB |
No variants for P39664
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P39664 | |||||
No associated diseases with P39664
7 regional properties for P39664
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PAS domain | 50 - 115 | IPR000014 |
| domain | Histidine kinase/HSP90-like ATPase | 279 - 398 | IPR003594 |
| domain | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain | 168 - 233 | IPR003661 |
| domain | Signal transduction histidine kinase-related protein, C-terminal | 316 - 330 | IPR004358-1 |
| domain | Signal transduction histidine kinase-related protein, C-terminal | 357 - 375 | IPR004358-2 |
| domain | Histidine kinase domain | 176 - 398 | IPR005467 |
| domain | PAS fold | 51 - 154 | IPR013767 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.13.3 | Protein-histidine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| phosphorelay sensor kinase activity | Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAWEFALGL | LTASLWRWAR | KWRSPVKVKP | MLAAVSSLEP | QLEQITTDLR | DRDRLLEDLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSFLLLDADN | LVLEANRSAR | VLLALPPEDY | CRPLLEVVRS | YELDRLVARC | RAANAPQTDR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WTLTPVNPDP | LQVVPQTPRP | VQGQAIPLSN | GQIGVLIEDR | QELVDLAQQR | NRWVSDVAHE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LKTPLTSIRL | LAEALRDRLQ | DEPQVWVDRL | LGETQRLGQL | VQDLLELSRL | EQGPSGLQKL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EAVDLVALLT | SVRNSLEPLA | EPLRLGWAYQ | GPEQGFVRGD | RQRLFRLWLN | LVDNAIRHSP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SGGCLYVELR | QRGDTWICDL | YDDGPGFADA | DLPYLFERFY | RGDPSRVRPA | AASSSSPGSG |
| 370 | 380 | 390 | 400 | 410 | |
| LGLAIARQVV | EAHQGRISAR | NHPVTGGAWL | RVQLPQEPSL | TPALKIGTGR | RSG |