Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P39547

Entry ID Method Resolution Chain Position Source
AF-P39547-F1 Predicted AlphaFoldDB

55 variants for P39547

Variant ID(s) Position Change Description Diseaes Association Provenance
s01-183768 2 Q>R No SGRP
s01-183812 17 E>K No SGRP
s01-183848 29 L>F No SGRP
s01-183854 31 E>K No SGRP
s01-183859 32 D>E No SGRP
s01-183861 33 T>I No SGRP
s01-183861 33 T>K No SGRP
s01-183867 35 N>S No SGRP
s01-183875 38 W>R No SGRP
s01-183884 41 I>V No SGRP
s01-183888 42 L>P No SGRP
s01-183890 43 N>Y No SGRP
s01-183898 45 I>M No SGRP
s01-183903 47 R>H No SGRP
s01-183906 48 C>Y No SGRP
s01-183912 50 P>L No SGRP
s01-183914 51 L>I No SGRP
s01-183917 52 M>V No SGRP
s01-183948 62 V>A No SGRP
s01-184067 102 N>D No SGRP
s01-184077 105 F>S No SGRP
s01-184203 147 Y>C No SGRP
s01-184229 156 K>E No SGRP
s01-184250 163 K>E No SGRP
s01-184293 177 G>D No SGRP
s01-184296 178 A>E No SGRP
s01-184310 183 S>P No SGRP
s01-184313 184 N>D No SGRP
s01-184316 185 T>A No SGRP
s01-184319 186 P>S No SGRP
s01-184323 187 A>E No SGRP
s01-184325 188 K>E No SGRP
s01-184326 188 K>I No SGRP
s01-184327 188 K>N No SGRP
s01-184328 189 E>K No SGRP
s01-184335 191 S>L No SGRP
s01-184341 193 E>V No SGRP
s01-184345 194 M>I No SGRP
s01-184343 194 M>L No SGRP
s01-184343 194 M>V No SGRP
s01-184347 195 V>G No SGRP
s01-184350 196 K>R No SGRP
s01-184353 197 P>L No SGRP
s01-184352 197 P>S No SGRP
s01-184356 198 Y>F No SGRP
s01-184361 200 F>L No SGRP
s01-184362 200 F>Y No SGRP
s01-184367 202 S>P No SGRP
s01-184376 205 V>I No SGRP
s01-184391 210 L>F No SGRP
s01-184412 217 H>D No SGRP
s01-184412 217 H>N No SGRP
s01-184416 218 K>I No SGRP
s01-184416 218 K>R No SGRP
s01-184444 227 K>N No SGRP

No associated diseases with P39547

No regional properties for P39547

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P39547

Functions

Description
EC Number
Subcellular Localization
  • Nucleus membrane ; Multi-pass membrane protein
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
fungal-type vacuole membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nuclear envelope The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQTPSENTDV KLDTLDEPSA HLIEENVALP EDTFNSYWSY ILNEIARCKP LMIMFLIPVC
70 80 90 100 110 120
LVLLITFFHD IKGILVFLVI SLILSIIILL IGITAFVSET LNKGFIIKLL VEVITRKPAV
130 140 150 160 170 180
GGKEWRIIAY NMNQYLFDHG IWHTPYYFFC EHRCHKFFKS LIKQTRSNAH LSSPTNGAEN
190 200 210 220 230
TQSNTPAKEV SNEMVKPYIF SSDPVLEAYL IKAAEIHKEA EFEYWRKQYP EVDLP