P39286

PR
Gene name
rsgA
Protein name
Small ribosomal subunit biogenesis GTPase RsgA
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b4161
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for P39286

Entry ID Method Resolution Chain Position Source
2YKR EM 980 A W 1-350 PDB
4A2I EM 1650 A V 35-337 PDB
5NO2 EM 516 A Z 34-346 PDB
5NO3 EM 516 A Z 34-346 PDB
5NO4 EM 516 A Z 34-346 PDB
5UZ4 EM 580 A Z 6-339 PDB
7BOI EM 298 A W 1-350 PDB
7NAR EM 300 A W 1-350 PDB
AF-P39286-F1 Predicted AlphaFoldDB

No variants for P39286

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P39286

No associated diseases with P39286

2 regional properties for P39286

Type Name Position InterPro Accession
domain RsgA GTPase domain 100 - 276 IPR010914
domain Circularly permuted (CP)-type guanine nucleotide-binding (G) domain 104 - 273 IPR030378

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Associates with 30S ribosomes (PubMed:14973029)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

6 GO annotations of molecular function

Name Definition
GDP binding Binding to GDP, guanosine 5'-diphosphate.
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
guanosine tetraphosphate binding Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
metal ion binding Binding to a metal ion.
rRNA binding Binding to a ribosomal RNA.

2 GO annotations of biological process

Name Definition
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKNKLSKGQ QRRVNANHQR RLKTSKEKPD YDDNLFGEPD EGIVISRFGM HADVESADGD
70 80 90 100 110 120
VHRCNIRRTI RSLVTGDRVV WRPGKPAAEG VNVKGIVEAV HERTSVLTRP DFYDGVKPIA
130 140 150 160 170 180
ANIDQIVIVS AILPELSLNI IDRYLVACET LQIEPIIVLN KIDLLDDEGM AFVNEQMDIY
190 200 210 220 230 240
RNIGYRVLMV SSHTQDGLKP LEEALTGRIS IFAGQSGVGK SSLLNALLGL QKEILTNDIS
250 260 270 280 290 300
DNSGLGQHTT TAARLYHFPH GGDVIDSPGV REFGLWHLEP EQITQGFVEF HDYLGLCKYR
310 320 330 340
DCKHDTDPGC AIREAVEEGK IAETRFENYH RILESMAQVK TRKNFSDTDD