P38909

PR
Gene name
CYC2 (YOR037W, OR26.30)
Protein name
Cytochrome c mitochondrial import factor CYC2
Names
Cytochrome c assembly flavoprotein CYC2
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR037W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P38909

Entry ID Method Resolution Chain Position Source
AF-P38909-F1 Predicted AlphaFoldDB

8 variants for P38909

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-402084 177 P>L No SGRP
s15-402137 195 D>N No SGRP
s15-402170 206 G>S No SGRP
s15-402179 209 V>I No SGRP
s15-402311 253 T>A No SGRP
s15-402498 315 N>S No SGRP
s15-402509 319 I>V No SGRP
s15-402555 334 S>N No SGRP

No associated diseases with P38909

2 regional properties for P38909

Type Name Position InterPro Accession
domain Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain 141 - 181 IPR008333
domain FAD-binding domain, ferredoxin reductase-type 63 - 184 IPR017927

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extrinsic component of mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
cytochrome-b5 reductase activity, acting on NAD(P)H Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

3 GO annotations of biological process

Name Definition
cytochrome c-heme linkage The linkage of cytochromes and other heme proteins to heme.
ergosterol biosynthetic process The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLWKNYVLSS SRITRRLHKS PRKSSFSKNF FITGCLLTVG AVSSYLTYRY TSERENKHEL
70 80 90 100 110 120
SPSYFVKYKI SHKRDIDSSH FLLEVTPLFK QKVNIWSLMT AENLWSVEIK QPEVMVVRNY
130 140 150 160 170 180
TPLPLKFNPA SKEIEILKDG DNADGKLSFY IKKYENGEVA RWLHHLPKGH IIEIRGPFID
190 200 210 220 230 240
YEFPHLPNEL KRSRDCLYMD NRNERGNNVR ENSQFIYQPY DIMMFTAGTG IVTALQLLLT
250 260 270 280 290 300
ESPFRGTIKL FHTDKNIKQL GPLYPILLRL QASNRVQLKI FETDRQTKQD VLKSIQKSIT
310 320 330 340 350 360
KPYPYKGLLP FSNVNNKNIM PVLALVCGPE SYISSISGRK YDLNQGPVGG LLSKEGWNSD
NVYKLS