P38852

PR
Gene name
LIN1 (YHR156C)
Protein name
Protein LIN1
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YHR156C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P38852

Entry ID Method Resolution Chain Position Source
AF-P38852-F1 Predicted AlphaFoldDB

11 variants for P38852

Variant ID(s) Position Change Description Diseaes Association Provenance
s08-412284 42 S>R No SGRP
s08-412130 94 D>N No SGRP
s08-412079 111 G>S No SGRP
s08-412051 120 G>D No SGRP
s08-411964 149 A>V No SGRP
s08-411951 153 D>E No SGRP
s08-411812 200 L>F No SGRP
s08-411754 219 K>R No SGRP
s08-411650 254 V>I No SGRP
s08-411602 270 I>F No SGRP
s08-411430 327 R>Q No SGRP

No associated diseases with P38852

1 regional properties for P38852

Type Name Position InterPro Accession
domain GYF domain 282 - 340 IPR003169

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Probably associated with chromatin
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
U5 snRNP A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKYTQYPNSS KLKRNSDRRE HDEKLSDELH NQSTIYEDEE LSRAEYDSDS DSSVEDSTDN
70 80 90 100 110 120
ENSGKEMDEK SYEKNEDHVE DHRKRKKSKI QLLDIAEFKK ENLADLDYQI GNSESKVEKG
130 140 150 160 170 180
VNIEPFNIDD EIKHGVFDKD GNYIKTENAT ENDQQDNEEW MNDVINTEEV NRLEKEQSVK
190 200 210 220 230 240
TQNSRHYMVH EALNLLKFFL VDENETVLES LGRLNKLRKI AISKKNKSLK YVIHGIELLS
250 260 270 280 290 300
DLINILEKKG FSEVYEYNRL KVQDAIEEEI FDDSSRIVNH KTKLWGFKWL NKLDEYHGLY
310 320 330
TNYEMSYWQK SYFKNSVIVK FHSEPDRDEN WIHVSCLSFM