Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P38545
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P38545-F1 | Predicted | AlphaFoldDB |
2 variants for P38545
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 40 | P>A | strain: IT04 [UniProt] | No | ||
| 196 | E>G | strain: IT04 [UniProt] | No |
No associated diseases with P38545
1 regional properties for P38545
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 10 - 158 | IPR005225 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| nucleocytoplasmic transport | The directed movement of molecules between the nucleus and the cytoplasm. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSQEYIPQY | KLILVGDGGV | GKTTFVKRHL | TGEFEKKYIP | TLGVEVHPLK | FQTNFGKTQF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVWDTAGQEK | FGGLRDGYYI | KSDCAIIMFD | VSSRITYKNV | PNWYRDITRV | CETIPMVLVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKVDVKDRQV | KSRQIQFHRK | RNLQYYDLSA | RSNYNFEKPF | LWLARRLSNQ | PNLVFVGEHA |
| 190 | 200 | 210 | |||
| KAPEFQIDLN | IVREAEKELE | QAAAVAIDEE | DIEN |