P38542
Gene name |
Bm1_44725 |
Protein name |
GTP-binding nuclear protein Ran |
Names |
GTPase Ran, Ras-like protein TC4 |
Species |
Brugia malayi (Filarial nematode worm) |
KEGG Pathway |
bmy:BM_BM4731 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P38542
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P38542-F1 | Predicted | AlphaFoldDB |
No variants for P38542
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P38542 | |||||
No associated diseases with P38542
1 regional properties for P38542
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 9 - 158 | IPR005225 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| embryo development ending in birth or egg hatching | The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. |
| nucleocytoplasmic transport | The directed movement of molecules between the nucleus and the cytoplasm. |
| oogenesis | The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATGDDIPTF | KLVLVGDGGT | GKTTFVKRHL | TGEFEKKYVA | TLGVEVHPLI | FHTNRGQIRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVWDTAGQEK | FGGLRDGYYI | QGQCAIIMFD | VTARVTYKNV | PNWHRDLVRV | CENIPIVLCG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKVDVKDRKV | KAKTITFHRK | KNLQYYDISA | KSNYNFEKPF | LWLARKLLGD | PNLEFVAMPA |
| 190 | 200 | 210 | |||
| LAPPEVQMDP | TMVAQYEQEI | AAAANAELPD | DDEDL |