Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P37375

Entry ID Method Resolution Chain Position Source
AF-P37375-F1 Predicted AlphaFoldDB

No variants for P37375

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P37375

No associated diseases with P37375

2 regional properties for P37375

Type Name Position InterPro Accession
domain Integrase, catalytic domain 326 - 513 IPR002104
domain Core-binding (CB) domain 216 - 302 IPR044068

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNASSKRKII SQSEISKKIA VMNEEMQGFW ANNSWDIRKC PHPSAIELSK NPALRNRWVR
70 80 90 100 110 120
FERVKNLWLR TELKYFYFYH LNNGIWNAKT VWIRKGTVIN KMLDFLDLKY PSITSITEVP
130 140 150 160 170 180
IDKAMTEYRT YLTKQGVRIT TTNYKITANQ EKTPVKANSY YVTNLKQFIE FIEDFYFDGE
190 200 210 220 230 240
EWDKDVWDRR NLPLPDDKVN PTQYEYTINF KGFRNTYFKQ LVKRYCKLRL NMDSFSYVSD
250 260 270 280 290 300
IAQKLKEFFN FLDIKFKHVQ RVHQLTRVEI EAYLSELNMM GIKPSTITGR ISILEGLFST
310 320 330 340 350 360
LHRLEWDDVP SKLLIYPEDY PKIPRAKPRF IDEFVLEQLN SHLDKLPEYI ATMTMIVQEC
370 380 390 400 410 420
GMRISELCTL KKGCLLEDKD GYYFLKYYQW KMKKEHIVPI SKEVVLLIKV REDKVSEEFP
430 440 450 460 470 480
DSEYLFPRKD GSPLKQETFR GELNKLAYEQ NIVDKLGEIY RFHAHAFRHS VGTRTINNGV
490 500 510 520 530 540
PQHIVQKFLG HESPEMTSRY AHIFDETLKN EFTKFQEKLV TNNGDVLNLD DDSEVDDVEL
550 560 570 580 590 600
QWFKKNINAQ VLPNGYCRLP VIAGGCPHAN ACLDCTHFCT SKQFLPQHEE QLERTEELLT
610 620
IAKDKQWQRQ IETNSRVKER LEQIIGSLTG