P37114
Gene name |
CYP73A3 |
Protein name |
Trans-cinnamate 4-monooxygenase |
Names |
Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H |
Species |
Medicago sativa (Alfalfa) |
KEGG Pathway |
|
EC number |
1.14.14.91: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P37114
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P37114-F1 | Predicted | AlphaFoldDB |
No variants for P37114
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P37114 | |||||
No associated diseases with P37114
1 regional properties for P37114
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 441 - 450 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.91 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| trans-cinnamate 4-monooxygenase activity | Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDLLLLEKTL | LALFIAATIA | VTISKLRGKR | FKLPPGPIPV | PIFGYWLQVG | DDLNHRNLTD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YAKRFGEIFL | LRMGQRNLVV | VSSPELAKEV | LHTQCVEFGS | RTRNVVFDIF | TGKGQDMVFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VYGEHWRKMR | RIMTVPFFTN | KVVQQYRYGW | ESEAESVVND | VKNNAEASVG | GIVIRKRLQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MMYNIMYRIM | FDRRFESEED | PLFVKLKALN | GERSRLAQSF | EYNYGDFIPI | LRPFLKGYLK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VCKEVKDRRL | QLFKDYFVDE | RKKLESTKST | TSNDGLKCAI | DHILDAQKKG | EINDDNVLYI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VENINVAAIE | TTLWSIEWGI | AELVNHQDIQ | NKVREEMDRV | LGPGHQVTEP | DLHKLPYLQA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VIKETLRLRM | AIPLLVPHMN | LHDPKLNGFD | IPAESKILVN | AWWLPNNPAH | WKKPEEFRPE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RFLEEESHVE | ANGNDFRYLP | FGVGRRSCPG | IILALPILGI | TIGRLVQNVE | LLPPPGQSKI |
| 490 | 500 | ||||
| DTSEKGGQFS | LHILKHSTIV | AKPRSF |