P36836

PR
Gene name
SLC15A1 (PEPT1)
Protein name
Solute carrier family 15 member 1
Names
Intestinal H(+)/peptide cotransporter, Oligopeptide transporter, small intestine isoform, Peptide transporter 1
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
ocu:100009186
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

652-707 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P36836

Entry ID Method Resolution Chain Position Source
AF-P36836-F1 Predicted AlphaFoldDB

No variants for P36836

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P36836

No associated diseases with P36836

2 regional properties for P36836

Type Name Position InterPro Accession
conserved_site PTR2 family proton/oligopeptide symporter, conserved site 70 - 94 IPR018456-1
conserved_site PTR2 family proton/oligopeptide symporter, conserved site 163 - 175 IPR018456-2

Functions

Description
EC Number
Subcellular Localization
  • Apical cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
spanning component of membrane The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.

3 GO annotations of molecular function

Name Definition
dipeptide transmembrane transporter activity Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
peptide:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.
tripeptide transmembrane transporter activity Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.

3 GO annotations of biological process

Name Definition
dipeptide import across plasma membrane The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tripeptide import across plasma membrane The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGMSKSLSCF GYPLSIFFIV VNEFCERFSY YGMRALLILY FRNFIGWDDN LSTVIYHTFV
70 80 90 100 110 120
ALCYLTPILG ALIADAWLGK FKTIVWLSIV YTIGQAVTSL SSVNELTDNN HDGTPDSLPV
130 140 150 160 170 180
HVAVCMIGLL LIALGTGGIK PCVSAFGGDQ FEEGQEKQRN RFFSIFYLAI NAGSLLSTII
190 200 210 220 230 240
TPMVRVQQCG IHVKQACYPL AFGIPAILMA VSLIVFIIGS GMYKKFKPQG NILSKVVKCI
250 260 270 280 290 300
CFAIKNRFRH RSKQFPKRAH WLDWAKEKYD ERLIAQIKMV TRVLFLYIPL PMFWALFDQQ
310 320 330 340 350 360
GSRWTLQATT MSGRIGILEI QPDQMQTVNT ILIIILVPIM DAVVYPLIAK CGLNFTSLKK
370 380 390 400 410 420
MTIGMFLASM AFVAAAILQV EIDKTLPVFP KANEVQIKVL NVGSENMIIS LPGQTVTLNQ
430 440 450 460 470 480
MSQTNEFMTF NEDTLTSINI TSGSQVTMIT PSLEAGQRHT LLVWAPNNYR VVNDGLTQKS
490 500 510 520 530 540
DKGENGIRFV NTYSQPINVT MSGKVYEHIA SYNASEYQFF TSGVKGFTVS SAGISEQCRR
550 560 570 580 590 600
DFESPYLEFG SAYTYLITSQ ATGCPQVTEF EDIPPNTMNM AWQIPQYFLI TSGEVVFSIT
610 620 630 640 650 660
GLEFSYSQAP SNMKSVLQAG WLLTVAVGNI IVLIVAGAGQ INKQWAEYIL FAALLLVVCV
670 680 690 700
IFAIMARFYT YVNPAEIEAQ FEEDEKKKNP EKNDLYPSLA PVSQTQM