P36589

PR
Gene name
cdc14 (SPBC24C6.07)
Protein name
Cell division control protein 14
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC24C6.07
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

168-239 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P36589

Entry ID Method Resolution Chain Position Source
AF-P36589-F1 Predicted AlphaFoldDB

No variants for P36589

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P36589

No associated diseases with P36589

3 regional properties for P36589

Type Name Position InterPro Accession
domain Protein kinase domain 19 - 319 IPR000719
active_site Serine/threonine-protein kinase, active site 149 - 161 IPR008271
binding_site Protein kinase, ATP binding site 25 - 48 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body
  • Localizes to the SPB prior to cytokinesis and leaves once septation is complete
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
new mitotic spindle pole body The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.

1 GO annotations of molecular function

Name Definition
protein kinase activator activity Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
septation initiation signaling The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDLLNNAKQ HLCMRNPKLI RIGLRQVESI VYHVAKPSHD DKIPREIFLK LQDSPLYNST
70 80 90 100 110 120
TPCIYALDSL LEYQQNEEAY EKNFQFIQKL IDDLLHVIEG LVLIHPKSQT LFEDKATLRL
130 140 150 160 170 180
FIHLLQPSQP SMLQVAAMKT LVCIMADRPL AIRLFEQING LQQICVVFKH KQTSQDTRFQ
190 200 210 220 230
ILEFFYFYLS PEPYSIDVIA YRKTRTEKQA YLSKYLSNVQ GLRDDLDKFQ PFGKLDETFD