P36557

PR
Gene name
basS (parB, pmrB, STM4291)
Protein name
Sensor protein BasS
Names
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM4291
EC number
2.7.13.3: Protein-histidine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

73-148 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P36557

Entry ID Method Resolution Chain Position Source
AF-P36557-F1 Predicted AlphaFoldDB

No variants for P36557

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P36557

No associated diseases with P36557

6 regional properties for P36557

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 249 - 356 IPR003594
domain HAMP domain 89 - 141 IPR003660
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 142 - 202 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 285 - 299 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 316 - 334 IPR004358-2
domain Histidine kinase domain 149 - 356 IPR005467

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

1 GO annotations of biological process

Name Definition
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFQRRAMTL RQRLMLTIGL ILLVFQLIST FWLWHESTEQ IQLFEQALRD NRNNDRHIMH
70 80 90 100 110 120
EIREAVASLI VPGVFMVSLT LLICYQAVRR ITRPLAELQK ELEARTADNL APIAIHSSTL
130 140 150 160 170 180
EIESVVSAIN QLVTRLTTTL DNERLFTADV AHELRTPLSG VRLHLELLSK THNVDVAPLI
190 200 210 220 230 240
ARLDQMMDSV SQLLQLARVG QSFSSGNYQE VKLLEDVILP SYDELNTMLE TRQQTLLLPE
250 260 270 280 290 300
SAADVVVRGD ATLLRMLLRN LVENAHRYSP EGTHITIHIS ADPDAIMAVE DEGPGIDESK
310 320 330 340 350
CGKLSEAFVR MDSRYGGIGL GLSIVSRITQ LHQGQFFLQN RTERTGTRAW VLLKKA