P36238

PR
Gene name
rplK
Protein name
50S ribosomal protein L11
Names
Species
Thermus thermophilus
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-147 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

12 structures for P36238

Entry ID Method Resolution Chain Position Source
2E34 NMR - A 1-147 PDB
2E35 NMR - A 1-147 PDB
2E36 NMR - A 1-147 PDB
2H8W NMR - A 1-147 PDB
2KLM Other - A 2-147 PDB
2NXN X-ray 240 A B 1-147 PDB
3CJQ X-ray 270 A B/E/H 2-147 PDB
3CJR X-ray 205 A B 1-147 PDB
3CJS X-ray 137 A B/C 1-72 PDB
3CJT X-ray 230 A B/D/F/H/J/L/N/P 1-147 PDB
4V67 X-ray 300 A BK/DK 1-147 PDB
AF-P36238-F1 Predicted AlphaFoldDB

No variants for P36238

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P36238

No associated diseases with P36238

2 regional properties for P36238

Type Name Position InterPro Accession
conserved_site Ribosomal protein L15, conserved site 111 - 141 IPR001196
domain Ribosomal protein L18e/L15P 27 - 144 IPR021131

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

2 GO annotations of molecular function

Name Definition
large ribosomal subunit rRNA binding Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKVVAVVKL QLPAGKATPA PPVGPALGQH GANIMEFVKA FNAATANMGD AIVPVEITIY
70 80 90 100 110 120
ADRSFTFVTK TPPASYLIRK AAGLEKGAHK PGREKVGRIT WEQVLEIAKQ KMPDLNTTDL
130 140
EAAARMIAGS ARSMGVEVVG APEVKDA