P36210
Gene name |
RPL12A (At3g27830, K16N12.4) |
Protein name |
50S ribosomal protein L12-1, chloroplastic |
Names |
CL12-A |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G27830 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P36210
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P36210-F1 | Predicted | AlphaFoldDB |
19 variants for P36210
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH11081326 | 18 | P>L | No | 1000Genomes | |
| ENSVATH02225126 | 21 | A>T | No | 1000Genomes | |
| ENSVATH00356887 | 23 | I>T | No | 1000Genomes | |
| ENSVATH05941088 | 27 | P>S | No | 1000Genomes | |
| ENSVATH02225127 | 31 | T>S | No | 1000Genomes | |
| tmp_3_10318690_T_G | 39 | F>V | No | 1000Genomes | |
| ENSVATH00356888 | 42 | G>A | No | 1000Genomes | |
| ENSVATH05941092 | 58 | A>S | No | 1000Genomes | |
| tmp_3_10318873_G_C | 100 | A>P | No | 1000Genomes | |
| tmp_3_10318883_C_A | 103 | A>E | No | 1000Genomes | |
| ENSVATH02225130 | 105 | A>S | No | 1000Genomes | |
| ENSVATH05941095 | 106 | V>I | No | 1000Genomes | |
| ENSVATH14038225 | 110 | A>S | No | 1000Genomes | |
| ENSVATH14038225 | 110 | A>T | No | 1000Genomes | |
| ENSVATH05941097 | 116 | A>T | No | 1000Genomes | |
| ENSVATH14038227 | 116 | A>V | No | 1000Genomes | |
| ENSVATH02225139 | 169 | I>M | No | 1000Genomes | |
| ENSVATH05941100 | 169 | I>V | No | 1000Genomes | |
| tmp_3_10319088_A_C | 171 | K>N | No | 1000Genomes |
No associated diseases with P36210
9 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast envelope | The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. |
| chloroplast nucleoid | The region of a chloroplast to which the DNA is confined. |
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
| chloroplast thylakoid membrane | The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
| plastid large ribosomal subunit | The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). |
| thylakoid | A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P36212 | RPL12C | 50S ribosomal protein L12-3, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASTTLSIAT | TIRSSSYPTL | ASINHFPSRT | TTIEFPSRFG | GGSSSTLTHR | ATHLRPIAAV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAPEKIEKIG | SEISSLTLEE | ARILVDYLQD | KFGVSPLSLA | PAAAAVAAPA | DGGAAAVVEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QTEFDVVINE | VPSSSRIAVI | KAVRALTSLA | LKEAKELIEG | LPKKFKEGIT | KDEAEEAKKT |
| 190 | |||||
| LEEAGAKVSI | A |