P35709

PR
Gene name
MBP2
Protein name
Eosinophil granule major basic protein 2
Names
MBP-2
Species
Cavia porcellus (Guinea pig)
KEGG Pathway
cpoc:100379574
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-132 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P35709

Entry ID Method Resolution Chain Position Source
AF-P35709-F1 Predicted AlphaFoldDB

No variants for P35709

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P35709

No associated diseases with P35709

3 regional properties for P35709

Type Name Position InterPro Accession
domain C-type lectin-like 99 - 233 IPR001304
conserved_site C-type lectin, conserved site 209 - 232 IPR018378
domain Eosinophil major basic protein, C-type lectin-like domain 117 - 234 IPR033816

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic granule
  • Matrix of eosinophil's large specific granule (crystalloid core)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.

2 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLLLLLALL VGAVSTRHLN VDTSSLQSLQ GEESLAQDGE TAEGATREAA SGVLMPLREE
70 80 90 100 110 120
VKEEMEGGSG SEDDPEEEEE EKEMESSSEL DMGPEDVQCP KEEDIVKFEG SPGCKICRYV
130 140 150 160 170 180
VLSVPKTFKQ AQSVCQRCFR GNLASIHSYN INLQVQRSSR ILNVAQVWIG GQLRGKGHHK
190 200 210 220 230
HFHWVDGTLW NFWYWAAGQP WRGNNSGRCV TLCARGGHWR RSHCGVRRAF SCSY