P35614
Gene name |
ERF1-3 (At3g26618, MFE16.17) |
Protein name |
Eukaryotic peptide chain release factor subunit 1-3 |
Names |
5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Hepatoma-associated antigen, HAb18G, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, Eukaryotic release factor 1-3, eRF1-3, Omnipotent suppressor protein 1 homolog 3, SUP1 homolog 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G26618 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P35614
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P35614-F1 | Predicted | AlphaFoldDB |
25 variants for P35614
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05927814 | 5 | E>D | No | 1000Genomes | |
| tmp_3_9788876_A_T | 8 | K>M | No | 1000Genomes | |
| tmp_3_9788887_A_C | 12 | I>L | No | 1000Genomes | |
| ENSVATH14024142 | 13 | W>* | No | 1000Genomes | |
| ENSVATH11025567 | 44 | A>S | No | 1000Genomes | |
| tmp_3_9789001_C_T | 50 | L>F | No | 1000Genomes | |
| tmp_3_9789004_G_T | 51 | A>S | No | 1000Genomes | |
| ENSVATH02213243 | 101 | D>E | No | 1000Genomes | |
| tmp_3_9789262_C_A | 137 | L>I | No | 1000Genomes | |
| tmp_3_9789326_C_T | 158 | T>I | No | 1000Genomes | |
| tmp_3_9789344_G_A | 164 | R>K | No | 1000Genomes | |
| tmp_3_9789452_T_A | 200 | V>E | No | 1000Genomes | |
| ENSVATH11025569 | 252 | N>Y | No | 1000Genomes | |
| tmp_3_9789628_G_A | 259 | G>R | No | 1000Genomes | |
| ENSVATH00353292 | 299 | G>A | No | 1000Genomes | |
| tmp_3_9789842_G_T | 330 | R>M | No | 1000Genomes | |
| tmp_3_9789849_G_C | 332 | E>D | No | 1000Genomes | |
| ENSVATH02213249 | 333 | L>V | No | 1000Genomes | |
| tmp_3_9789892_G_A | 347 | G>R | No | 1000Genomes | |
| ENSVATH11025572 | 362 | T>N | No | 1000Genomes | |
| ENSVATH11025571 | 362 | T>S | No | 1000Genomes | |
| ENSVATH05927823 | 369 | Q>L | No | 1000Genomes | |
| ENSVATH05927824 | 372 | M>K | No | 1000Genomes | |
| tmp_3_9790008_T_G | 385 | F>L | No | 1000Genomes | |
| ENSVATH05927826 | 427 | D>E | No | 1000Genomes |
No associated diseases with P35614
No regional properties for P35614
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P35614 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| translation release factor complex | A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| sequence-specific mRNA binding | Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif. |
| translation release factor activity | Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. |
| translation release factor activity, codon specific | A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translational termination | The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. |
| translational termination | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADQESDKNI | EIWKIKKLIK | GLETARGNGT | SMISLIMPPR | DQVARVTKML | ADEYGTASNI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KSRVNRQSVL | SAITSAQQRL | KLYNKVPPNG | LVLYTGTIVT | DDGKEKKVTI | DFEPFKPINA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SLYLCDNKFH | TEPLNELLES | DDKFGFIVMD | GNGTLFGTLS | GNTREVLHKF | TVDLPKKHGR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GGQSALRFAR | LRMEKRHNYV | RKTAELATQF | YINPATSQPN | VSGLILAGSA | DFKTELSQSE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFDPRLQAKI | LNVVDVSYGG | ENGFNQAIEL | SAEILSNVKF | IQEKKLIGKY | FEEISQDTGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YVFGVEDTLK | ALEMGAVETL | IVWENLDINR | YELKNNTTGE | IVIKHLGKDQ | ENNQSNFHDA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ETNAELEVQE | KMPLLEWFAN | EYKRFGCTLE | FVTNKSQEGS | QFCRGFGGIG | GLLRYQLDMR |
| 430 | |||||
| TFDELSDGEV | YEDSD |