P35447

PR
Gene name
spon1
Protein name
Spondin-1
Names
F-spondin
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

437-508 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P35447

Entry ID Method Resolution Chain Position Source
AF-P35447-F1 Predicted AlphaFoldDB

No variants for P35447

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P35447

No associated diseases with P35447

9 regional properties for P35447

Type Name Position InterPro Accession
repeat Thrombospondin type-1 (TSP1) repeat 436 - 489 IPR000884-1
repeat Thrombospondin type-1 (TSP1) repeat 495 - 549 IPR000884-2
repeat Thrombospondin type-1 (TSP1) repeat 552 - 605 IPR000884-3
repeat Thrombospondin type-1 (TSP1) repeat 608 - 662 IPR000884-4
repeat Thrombospondin type-1 (TSP1) repeat 664 - 717 IPR000884-5
repeat Thrombospondin type-1 (TSP1) repeat 750 - 803 IPR000884-6
domain Reeler domain 24 - 190 IPR002861
domain Spondin, N-terminal 191 - 383 IPR009465
domain Spondin-like TSP1 domain 665 - 716 IPR044004

Functions

Description
EC Number
Subcellular Localization
  • Secreted, extracellular space, extracellular matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLIFQPLFW QYVATSYALM VLGFLDETVE KAIKSEGYCS RILRAQGGTR KEGYNEFSMR
70 80 90 100 110 120
VEGDPEFYKP GNTYRVTILA VSPAYFRGFT LIALKEGKEG EKEEDHAGSF QIIDEEDTQF
130 140 150 160 170 180
MSNCPVAVTE STPRRRTRIQ VFWTAPSIGT GCVILKASIV QKKIIYFQDE GSLTKRMCEL
190 200 210 220 230 240
DLTLEGGNEK TIPDCCACGT AKYRLTFYGN WSEKAHPKDY PRRANHWSAI IGGSHSGEYV
250 260 270 280 290 300
LWEYGQASDG VKQVAELGSP VKMEEEIRQK GDEVLTVIKA KAQWPAWQPL NVRAAPSAEF
310 320 330 340 350 360
SVDRSRHLMS FLAMMGPSPD WNVGLTSEDL CTKECGWVQK VVQDLIPWDA GTDSGVTYES
370 380 390 400 410 420
PNKPTIPQDK IRPLTSLDHP QSPSMTRGGP IIPIARVVIE RIARKGEQCN IIPDNVDDIV
430 440 450 460 470 480
ADLVTEEKDE DDTPETCIYS NWSPWSACSS ATCDKGKRMR QRMLKAQLDL SVPCPDTQDF
490 500 510 520 530 540
EPCMGPGCSD DEASTCMMSE WITWSPCSAS CGMGIEVRER YVKQFPEDGS LCKVPTEETE
550 560 570 580 590 600
KCIVNEECEP SSCIVTEWAE WEECSATCRM GMKKRHRMIK MTPADGSMCK ADTTEVEKCM
610 620 630 640 650 660
MPECHTIPCV LSPWSEWSDC SVTCGKGTRT RQRMLKSPSE LGDCNEELEL KQVEKCMLPE
670 680 690 700 710 720
CPISCELTEW SYWSECNKSC GKGHMIRTRM ITMEPQFGGA VCPETVQRKK CRLRKCQKSS
730 740 750 760 770 780
GNERRHLKDA REKRRSEKIK EDSDGEQYPV CKMKPWTAWT ECTKFCGGGI QERFMTVKKR
790 800
FKSSQFTSCK DKKEIRACNV HPC