Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P35357

Entry ID Method Resolution Chain Position Source
AF-P35357-F1 Predicted AlphaFoldDB

No variants for P35357

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P35357

No associated diseases with P35357

3 regional properties for P35357

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 54 - 306 IPR017452
domain Rhodopsin, N-terminal 2 - 37 IPR019477
binding_site Visual pigments (opsins) retinal binding site 290 - 306 IPR027430

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.

2 GO annotations of biological process

Name Definition
phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNGTEGINFY VPLSNKTGLV RSPFEYPQYY LADPWKFKVL SFYMFFLIAA GMPLNGLTLF
70 80 90 100 110 120
VTFQHKKLRQ PLNYILVNLA AANLVTVCCG FTVTFYASWY AYFVFGPIGC AIEGFFATIG
130 140 150 160 170 180
GQVALWSLVV LAIERYIVIC KPMGNFRFSA THAIMGIAFT WFMALACAGP PLFGWSRFIP
190 200 210 220 230 240
EGMQCSCGPD YYTLNPDFHN ESYVIYMFIV HFTVPMVVIF FSYGRLVCKV REAAAQQQES
250 260 270 280 290 300
ATTQKAEKEV TRMVILMVLG FLLAWTPYAA TAIWIFTNRG AAFSVTFMTI PAFFSKSSSI
310 320 330 340 350
YNPIIYVLLN KQFRNCMVTT ICCGKNPFGD EDVSSSVSQS KTEVSSVSSS QVAPA