P34877

PR
Gene name
scrFIAM
Protein name
Type II methyltransferase M1.ScrFI
Names
M1.ScrFI, Cytosine-specific methyltransferase ScrFIA, Modification methylase ScrFIA, M.ScrFI-A, M.ScrFIA
Species
Lactococcus lactis subsp cremoris (Streptococcus cremoris)
KEGG Pathway
EC number
2.1.1.37: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P34877

Entry ID Method Resolution Chain Position Source
AF-P34877-F1 Predicted AlphaFoldDB

No variants for P34877

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34877

No associated diseases with P34877

3 regional properties for P34877

Type Name Position InterPro Accession
domain Cro/C1-type helix-turn-helix domain 15 - 73 IPR001387
active_site DNA methylase, C-5 cytosine-specific, active site 141 - 153 IPR018117
conserved_site DNA methylase, C-5 cytosine-specific, conserved site 362 - 380 IPR031303

Functions

Description
EC Number 2.1.1.37 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA (cytosine-5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTISRNTGT EISIMIKEKR LRLNMTQKEL ADAVGMSKNG DRTIRRWENG ETCPSQLEIS
70 80 90 100 110 120
AILRFPEIAP FENRKTAKYK MIDLFAGIGG TRLGFHQTEK VKSVFSSEID KFAIKTYKAN
130 140 150 160 170 180
FGDEPHGDIT KIDEKDIPDH DILVGGFPCQ AFSQAGKKLG FDDTRGTLFF EIARIIKEKR
190 200 210 220 230 240
PKAFLLENVK NLKTHDKGRT FKTILNTLEE LDYEVHTALF KARDFGLPQN RERIYIVGFD
250 260 270 280 290 300
RKSISNYSDF QMPTPLQEKT RVGNILESVV DDKYTISDKL WDGHQRRKTE NKKNGKGFGY
310 320 330 340 350 360
TLFNQDSEYT NTLSARYYKD GSEILIEQKN KNPRKITPRE AARLQGFPEN FIIPVSDTQA
370 380
YKEFGNSVAV PTIHAIAEKM LEVLEKSKK