P34257

PR
Gene name
tc3a (B0303.5)
Protein name
Transposable element Tc3 transposase
Names
Species
Caenorhabditis elegans
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

17-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P34257

Entry ID Method Resolution Chain Position Source
1TC3 X-ray 245 A C 2-52 PDB
1U78 X-ray 269 A A 1-135 PDB
AF-P34257-F1 Predicted AlphaFoldDB

No variants for P34257

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34257

No associated diseases with P34257

2 regional properties for P34257

Type Name Position InterPro Accession
domain Tc3 transposase, DNA binding domain 3 - 52 IPR025898
domain Tc1-like transposase, DDE domain 140 - 290 IPR038717

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPRGSALSDT ERAQLDVMKL LNVSLHEMSR KISRSRHCIR EYLKDPVSYG TSKRAPRRKA
70 80 90 100 110 120
LSVRDERNVI RAASNSCKTA RDIRNELQLS ASKRTILNVI KRSGVIVRQK LRPAPLLSAD
130 140 150 160 170 180
HKLKRLEFAK NNMGTNWSKV VFSDEKKFNL DGPDGCRYYW RDLRKEPMVF SRRNFGGGTV
190 200 210 220 230 240
MVWGAFTEKK KLEIQFVSSK MNSTDYQNVL ELELSKYLRH YSRKDFRFQQ DNATIHVSNS
250 260 270 280 290 300
TRDYFKLKKI NLLDWPARSP DLNPIENLWG ILVRIVYAQN KTYPTVASLK QGILDAWKSI
310 320
PDNQLKSLVR SMEDRLIEII RTQGNPINY