P34232

PR
Gene name
MTR2 (YKL186C)
Protein name
mRNA transport regulator MTR2
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YKL186C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

85-156 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P34232

Entry ID Method Resolution Chain Position Source
1OF5 X-ray 280 A B 1-184 PDB
4WWU X-ray 330 A C/F/I/L 1-184 PDB
8HBN EM 381 A B 1-184 PDB
8HFR EM 264 A Bt/DK/FR 1-184 PDB
AF-P34232-F1 Predicted AlphaFoldDB

No variants for P34232

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34232

No associated diseases with P34232

No regional properties for P34232

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P34232

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nuclear pore central transport channel The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
nuclear RNA export factor complex A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

6 GO annotations of biological process

Name Definition
mRNA export from nucleus The directed movement of mRNA from the nucleus to the cytoplasm.
nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm.
poly(A)+ mRNA export from nucleus The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.
ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.
ribosomal small subunit export from nucleus The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTNSNTMVM NDANQAQITA TFTKKILAHL DDPDSNKLAQ FVQLFNPNNC RIIFNATPFA
70 80 90 100 110 120
QATVFLQMWQ NQVVQTQHAL TGVDYHAIPG SGTLICNVNC KVRFDESGRD KMGQDATVPI
130 140 150 160 170 180
QPNNTGNRNR PNDMNKPRPL WGPYFGISLQ LIIDDRIFRN DFNGVISGFN YNMVYKPEDS
LLKI