P34118

PR
Gene name
mvpA (DDB_G0269156)
Protein name
Major vault protein alpha
Names
MVP-alpha
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0269156
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

394-464 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P34118

Entry ID Method Resolution Chain Position Source
AF-P34118-F1 Predicted AlphaFoldDB

No variants for P34118

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34118

No associated diseases with P34118

16 regional properties for P34118

Type Name Position InterPro Accession
repeat Major vault protein, N-terminal 56 - 116 IPR002499-1
repeat Major vault protein, N-terminal 117 - 168 IPR002499-2
repeat Major vault protein, N-terminal 169 - 221 IPR002499-3
repeat Major vault protein, N-terminal 222 - 277 IPR002499-4
repeat Major vault protein, N-terminal 279 - 328 IPR002499-5
repeat Major vault protein, N-terminal 329 - 380 IPR002499-6
repeat Major vault protein, N-terminal 381 - 433 IPR002499-7
domain Major vault protein, shoulder domain 494 - 644 IPR021870
domain Major vault protein repeat domain 3 442 - 503 IPR040989
domain Major vault protein repeat domain 2 50 - 109 IPR041134-1
domain Major vault protein repeat domain 2 273 - 318 IPR041134-2
domain Major vault protein repeat domain 4 377 - 427 IPR041136
domain Major vault protein repeat domain 113 - 153 IPR041139-1
domain Major vault protein repeat domain 166 - 205 IPR041139-2
domain Major vault protein repeat domain 218 - 262 IPR041139-3
domain Major vault protein repeat domain 325 - 365 IPR041139-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
response to bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADLNSVIRI KPFHFIHVLD NNTNVTRVEV GPQTFTRQDH EKLVSGPEPM IMIPQRNYCT
70 80 90 100 110 120
ISNPVVRNEN GSLVLDEYGQ VKLRHGDEEI RFSQEPFPLY PGEKISGKVT ALQVVAPLKA
130 140 150 160 170 180
LRLRALRDFT EAKVTHVAGD EWLFEGPATY LPRIDVRIEE EIKATIIGPN QALKLRANKA
190 200 210 220 230 240
CSDRSGVARK AGEEWLVRQH GAYLPGVDEK VVEIVNAYVL TDKKALHLKA TKTFLDETRK
250 260 270 280 290 300
TQRKAGEEWL VVSTDAETHI PDVYEQVVGE VHITTLSNRQ YCVVLDPIGA NGKPQLGHKQ
310 320 330 340 350 360
LRKGELAFFL NPGESLEGNK IHNIYVLTEQ EALLLRAKET FSIDGESHLA GDRWMIYGPC
370 380 390 400 410 420
DYVPPVQVEV VEKRESIPLD ENEGIYVRDI KTGKVASIKG QSYMLKANEE LWEKVLPRTV
430 440 450 460 470 480
EEVLAKESLN PEFTDNRDST RVVTYRAPHN SAVQIYDYKE KKSRVVFGPD LVMLGPDEHF
490 500 510 520 530 540
TVLSLSGDKP KRPHQIKAIA LFLGPDFMTD VVIVETSDHA RLSLKLSYNW EFKVDRSKIE
550 560 570 580 590 600
DAQKIFQVPD FVGDSCKAIA SRVRGAVAAV SFDDFHKRSA EVIRQSVFGL DESGEVRKNF
610 620 630 640 650 660
SFNSNNLVIT NIDIQSVEPV DQRTRDSLQK SVQLAIEITT KSQEAAARHE AERLEQGARG
670 680 690 700 710 720
RLERQKIHDE AQAELARKDL LQLQAQSAAV ESTGQATAEA QATAEAANIA AEANVKQAEL
730 740 750 760 770 780
KAQATKIRSE SEISLLKAKR ENELSYQKSI DELELTKQSD LAEIEASKFK AIVESIGRDT
790 800 810 820 830 840
LKSIACAGNE MQAKLLQGLG LKSFMITDGK SPLNLFDTAN GIIGNNNQMV NMSNAAKQSG
RRN