P33950

PR
Gene name
hbpA (dppA, HI_0853)
Protein name
Heme-binding protein A
Names
Hemin-binding lipoprotein
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0853
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P33950

Entry ID Method Resolution Chain Position Source
AF-P33950-F1 Predicted AlphaFoldDB

5 variants for P33950

Variant ID(s) Position Change Description Diseaes Association Provenance
48 K>NS strain: DL42 [UniProt] No
181 T>N strain: DL42 [UniProt] No
240 H>N strain: DL42 [UniProt] No
343 T>I strain: DL42 [UniProt] No
375 A>V strain: DL42 [UniProt] No

No associated diseases with P33950

2 regional properties for P33950

Type Name Position InterPro Accession
domain Solute-binding protein family 5 domain 85 - 465 IPR000914
conserved_site Solute-binding protein family 5, conserved site 90 - 112 IPR023765

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Lipid-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.

1 GO annotations of molecular function

Name Definition
peptide transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
dipeptide transport The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
peptide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLKATLTLA AATLVLAACD QSSSANKSTA QTEAKSSSNN TFVYCTAKAP LGFSPALIIE
70 80 90 100 110 120
GTSYNASSQQ VYNRLVEFKK GSTDIEPALA ESWEISDDGL SYTFHLRKGV KFHTTKEFTP
130 140 150 160 170 180
TRDFNADDVV FSFQRQLDPN HPYHNVSKGT YPYFKAMKFP ELLKSVEKVD DNTIRITLNK
190 200 210 220 230 240
TDATFLASLG MDFISIYSAE YADSMLKAGK PETLDSRPVG TGPFVFVDYK TDQAIQYVAH
250 260 270 280 290 300
ENYWKGRTPL DRLVISIVPD ATTRYAKLQA GTCDLILFPN VADLAKMKTD PKVQLLEQKG
310 320 330 340 350 360
LNVAYIAFNT EKAPFDNVKV RQALNYAVDK KAIIEAVYQG AGTSAKNPLP PTIWSYNDEI
370 380 390 400 410 420
QDYPYDPEKA KQLLAEAGYP NGFETDFWIQ PVIRASNPNP KRMAELIMAD WAKIGVKTNP
430 440 450 460 470 480
VTYEWADYRK RAKEGELTAG IFGWSGDNGD PDNFLSPLLG SSNIGNSNMA RFNNSEFDAL
490 500 510 520 530 540
LNEAIGLTNK EERAKLYKQA QVIVHNQAPW IPVAHSVGFA PLSPRVKGYV QSPFGYDAFY
GVSVDGK