P33871

PR
Gene name
C16L (F12L)
Protein name
Protein F12
Names
Species
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)
KEGG Pathway
vg:1486572
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

325-395 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P33871

Entry ID Method Resolution Chain Position Source

No variants for P33871

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P33871

No associated diseases with P33871

No regional properties for P33871

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P33871

Functions

Description
EC Number
Subcellular Localization
  • Virion membrane
  • Host endosome
  • Associates with the membrane of IEV particles, but not intracellular mature virus (IMV), cell-associated enveloped virus (CEV) or EEV
  • Colocalizes with microtubules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
host cell endosome A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
virion membrane The lipid bilayer surrounding a virion.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLNRVQILMK TANNYETIEI LRNYLRLYII LARNEEGHGI LIYDDNIDSI MSMMNITRLE
70 80 90 100 110 120
VIGLTTHCTK LRSSPPIPMS RLFMDEIDHE SYYSPKTSDY PLIDIIRKRS HEQGDIALAL
130 140 150 160 170 180
KRYCIENTDS ISEINEWLSS KGLACYRFVK FNDYRKQMYR KFSKCTIVDS MIIGHIGHHY
190 200 210 220 230 240
IWIKNLETYT RPEIDVLPFD IKYISRDELW AQISSSLDQT HIKTITVSVY GAITDNGPMP
250 260 270 280 290 300
YMISTYPGNT FVNFNSVKDL ILNFLDWIKD IMTSTRTIIL VGYMSNLFDI PLLTVYWPNN
310 320 330 340 350 360
CGWKIYNNIL ISSDGARVIW MDAYKFSCGL SLQDYCYHWG SKPESRPFDL IKKIDAKRNI
370 380 390 400 410 420
KSWVKESMTS LKSLYEAFET QSGALEVLMS PCRMFSFSRI EDMFLTSVIN RVSKNTGMGM
430 440 450 460 470 480
YYPTNDISSL FIESSICLDY IIVNNQKSNK YRIKSVLDII SSKQYPAGRP NYVKNGTKGK
490 500 510 520 530 540
LYIALCKVTV PTNDHIPVVY HDDDNTTTFI TVLTSVDIET ATRAGYSIVE LGALQWDDNI
550 560 570 580 590 600
PELKDCLLDS IKMIYDLNTV TTNNLLEQLI ENINFNNSSI ILLFYTFAIS YCRAFIYSIM
610 620 630
ETIDPVYISQ FSYKELYIRS SYKDINEVMS QMVKL