Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P33652
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2WUQ | X-ray | 180 A | A/B | 2-312 | PDB |
| AF-P33652-F1 | Predicted | AlphaFoldDB |
No variants for P33652
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P33652 | |||||
No associated diseases with P33652
1 regional properties for P33652
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Beta-lactamase class A, catalytic domain | 23 - 282 | IPR045155 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-lactamase activity | Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| beta-lactam antibiotic catabolic process | The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. |
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLNSESLLRE | LRDALHEGGL | TGSFLVRDLY | TGEELGIDPD | TELPTASLVK | LPLALATLER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IRLGEVDGAQ | QIEVAPGRIT | TPGPTGLSRF | RHPARVAVDD | LLYLSTSVSD | GTASDALFEI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TPPAQVEQMV | REWGFRDLTV | RHSMRELSET | PAERFESADA | HLAHALAISA | GTSGRGHRVP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QLDVARANTG | TARAFVDLLE | ALWAPVLTGP | RPGRTSRALP | PEPAARLREL | MAANLLRHRL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| APDFASDAAT | WSSKTGTLLN | LRHEVGVVEH | ADGQVFAVAV | LTESQVPADS | QPGAEALMAQ |
| 310 | |||||
| VARRLRDRLR | EW |