Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P33621
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P33621-F1 | Predicted | AlphaFoldDB |
No variants for P33621
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P33621 | |||||
No associated diseases with P33621
No regional properties for P33621
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P33621 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chylomicron | A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. |
| high-density lipoprotein particle | A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid binding | Binding to a lipid. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid transport | The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
| lipoprotein metabolic process | The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFLKAVVLTL | ALVAVTGARA | EVSADQVATV | MWDYFSQLSS | NAKEAVEHLQ | KSELTQQLNA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LFQDKLGEVN | TYAGDLQKKL | VPFATELHER | LAKDSEKLKE | EIRKELEEVR | ARLLPHANEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQKIGENVRE | LQQRLEPYTD | QLRTQVNTQT | EQLRRQLTPY | AQRMERVLRE | NADSLQTSLR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PHADQLKAKI | DQNVEELKER | LTPYADEFKV | KIDQTVEELR | RSLAPYAQDA | QEKLNHQLEG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAFQMKKNAE | ELKARISASA | EELRQRLAPL | AEDMRGNLRG | NTEGLQKSLA | ELGGHLDRHV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEFRLRVEPY | GENFNKALVQ | QMEQLRQKLG | PHAGDVEGHL | SFLEKDLRDK | VNSFFSTFKE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KESQDNTLSL | PEPEQQREQQ | QEQQQEQEQE | QQQQQEQQQQ | QEQQREQQQQ | EQQQEQQQEQ |
| VQMLAPLES |