Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P33263

Entry ID Method Resolution Chain Position Source
AF-P33263-F1 Predicted AlphaFoldDB

No variants for P33263

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P33263

No associated diseases with P33263

1 regional properties for P33263

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 428 - 437 IPR017972

Functions

Description
EC Number 1.14.14.1 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Endoplasmic reticulum membrane; Peripheral membrane protein
  • Microsome membrane; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.

3 GO annotations of molecular function

Name Definition
aromatase activity Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDAFVVLVFI LSCLFLLSLW RQSSERGKLP PGPTPLPIIG NFLQIDVKDI SGSLTNFSKV
70 80 90 100 110 120
YGPVFTLYLG MKPTVVLHGY EAVKEALIDH GEEFAGRGSF PVAERVNKGL GIVFSNGSRW
130 140 150 160 170 180
KETRRFSLMT LRNLGMGKRS IEDRVQEEAQ CLVEELRKTN GSPCDPTFIL GCAPCNVICS
190 200 210 220 230 240
IIFQNRFDYK DKDFLTFMKK LNENARILSS PWFQVCNNFP LLIDYCPGSH HRITKNINYI
250 260 270 280 290 300
RSYLSEKMKE HQESLDVANP RDFIDYYLIK LKQGNYNQQS EFSPENLATT VSDLFAAGTE
310 320 330 340 350 360
TTSTTLRYAL LLLLKHPHVT AKVQEEIDQV VGRHRNPCMQ DRSHMPYTDA MIHEVQRFID
370 380 390 400 410 420
LIPTNLPHAV TCDIKFRDYF IPKGTTIITS LSSVLHDSKE FPNPEVFDPG HFLDKNGNFK
430 440 450 460 470 480
KSDYFMPFST GKRMCAGEGL ARMELFLFLT TILQNFKLKS LVHPKDIDTT PVLNGFASLP
PSYQLCFIPV