P33059

PR
Gene name
H3L (I3L)
Protein name
Envelope protein H3
Names
Ag35, Virion envelope protein p35
Species
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)
KEGG Pathway
vg:1486441
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P33059

Entry ID Method Resolution Chain Position Source

No variants for P33059

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P33059

No associated diseases with P33059

No regional properties for P33059

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P33059

Functions

Description
EC Number
Subcellular Localization
  • Virion membrane ; Single-pass membrane protein
  • Component of the mature virion (MV) membrane
  • Becomes membrane associated presumably during virus maturation
  • The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
viral envelope The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
virion membrane The lipid bilayer surrounding a virion.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
virion attachment to host cell The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATVNKTPVI VVPVIDRPPS ETFPNLHEHI NDQKFDDVKD NEVMPEKRNV VIVKDDPDHY
70 80 90 100 110 120
KDYAFIHWTG GNIRNDDKYT HFFSGFCNTM CTEETKRNIA RHLALWDSKF FTELENKKVE
130 140 150 160 170 180
YVVIVENDNV IEDITFLRPV LKAMHDKKID ILQMREIITG NKVKTELVMD KNHVIFTYTG
190 200 210 220 230 240
GYDVSLSAYI IRVTTALNIV DEIIKSGGLS SGFYFEIARI ENEIKINRQI MDNSAKYVEH
250 260 270 280 290 300
DPRLVAEHRF ENMKPNFWSR IGTAAVKRYP GVMYAFTTPL ISFFGLFDIN VIGLIVILFI
310 320
MFMLIFNVKS KLLWFLTGTF VTAFI