P32963
Gene name |
chy1 |
Protein name |
Cyanide hydratase |
Names |
CHT, Cyanide-degrading nitrilase, Formamide hydrolyase |
Species |
Gibberella baccata (Fusarium lateritium) |
KEGG Pathway |
|
EC number |
4.2.1.66: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P32963
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P32963-F1 | Predicted | AlphaFoldDB |
No variants for P32963
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P32963 | |||||
No associated diseases with P32963
3 regional properties for P32963
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Nitrilase/cyanide hydratase, conserved site | 38 - 53 | IPR000132-1 |
| conserved_site | Nitrilase/cyanide hydratase, conserved site | 159 - 172 | IPR000132-2 |
| domain | Carbon-nitrogen hydrolase | 6 - 292 | IPR003010 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.66 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cyanide hydratase activity | Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. |
| nitrilase activity | Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cyanide catabolic process | The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAITKYKAAA | VTSEPGWFDL | EGGVRKTIDF | INEAGEAGCK | FVAFPEVWIP | GYPYWMWKVT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YLQSLPMLKR | YRENSMAVDS | EEMRRIRRAA | RDNQIFVSLG | FSEIDHATLY | LSQVLIGPDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVINHRRKIK | PTHVEKLVYG | DGSGDTFMSV | SETEIGRVGQ | LNCWENMNPF | LKSLNVSAGE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QVHVAAWPVY | PGKERQVHPD | PATNYADPAS | DLVTPEYAIE | TGTWTLAPFQ | RLSVEGLKIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TPEGVEPETD | PSVYNGHARI | YRPDGSLVVK | PEKDFDGLLF | VDIDLNECHL | TKVLADFAGH |
| 310 | 320 | 330 | 340 | 350 | |
| YMRPDLIRLL | VDTRRKKLIT | EADPNGSIAT | YSTRQRLGLD | KPLSKKEGDE | TTDVL |