AiPD: Autoinhibited Protein Database

Gene name	YME2 (PRP12, RNA12, YMR302C, YM9952.04C)
Protein name	Mitochondrial escape protein 2
Names	Protein RNA12
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YMR302C
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

11-95 (Predicted disordered autoinhibitory region) PR

11-95 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-P32843-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s13-872542	28	G>D	No	SGRP
s13-872369	86	T>A	No	SGRP
s13-872116	170	N>S	No	SGRP
s13-872092	178	A>V	No	SGRP
s13-871879	249	I>T	No	SGRP
s13-871807	273	R>I	No	SGRP
s13-871802	275	G>S	No	SGRP
s13-871559	356	Q>E	No	SGRP
s13-871555	357	R>T	No	SGRP
s13-871472	385	I>V	No	SGRP
s13-871358	423	P>S	No	SGRP
s13-871354	424	M>K	No	SGRP
s13-871298	443	D>N	No	SGRP
s13-871216	470	R>Q	No	SGRP
s13-871193	478	S>A	No	SGRP
s13-871184	481	S>A	No	SGRP
s13-870784	614	P>L	No	SGRP
s13-870766	620	T>I	No	SGRP
s13-870719	636	K>E	No	SGRP
s13-870587	680	V>L	No	SGRP
s13-870454	724	H>R	No	SGRP
s13-870242	795	G>S	No	SGRP
s13-870127	833	A>V	No	SGRP

Type	Name	Position	InterPro Accession
domain	RNA recognition motif domain	199 - 268	IPR000504
domain	Mitochondrial escape protein 2, C-terminal	364 - 814	IPR018850
domain	Yme2, RNA recognition motif	194 - 276	IPR034260

		Description
EC Number
Subcellular Localization	Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
integral component of mitochondrial inner membrane	The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

Name	Definition
RNA binding	Binding to an RNA molecule or a portion thereof.

Name	Definition
mitochondrial genome maintenance	The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins