P32714
Gene name |
mdtP (yjcP, b4080, JW4041) |
Protein name |
Multidrug resistance outer membrane protein MdtP |
Names |
|
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b4080 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P32714
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P32714-F1 | Predicted | AlphaFoldDB |
No variants for P32714
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P32714 | |||||
No associated diseases with P32714
No regional properties for P32714
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P32714 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell outer membrane | A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| transporter complex | A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| efflux transmembrane transporter activity | Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MINRQLSRLL | LCSILGSTTL | ISGCALVRKD | SAPHQQLKPE | QIKLADDIHL | ASSGWPQAQW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WKQLNDPQLD | ALIQRTLSGS | HTLAEAKLRE | EKAQSQADLL | DAGSQLQVAA | LGMLNRQRVS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ANGFLSPYSM | DAPALGMDGP | YYTEATVGLF | AGLDLDLWGV | HRSAVAAAIG | AHNAALAETA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AVELSLATGV | AQLYYSMQAS | YQMLDLLEQT | HDVIDYAVKA | HQSKVAHGLE | AQVPFHGARA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QILAVDKQIV | AVKGQITETR | ESLRALIGAG | ASDMPEIRPV | ALPQVQTGIP | ATLSYELLAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RPDLQAMRWY | VQASLDQVDS | ARALFYPSFD | IKAFFGLDSI | HLHTLFKKTS | RQFNFIPGLK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPLFDGGRLN | ANLEGTRAAS | NMMIERYNQS | VLNAVRDVAV | NGTRLQTLND | EREMQAERVE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ATRFTQRAAE | AAYQRGLTSR | LQATEARLPV | LAEEMSLLML | DSRRVIQSIQ | LMKSLGGGYQ |
| AGPVVEKK |