P32522
Gene name |
PET309 (YLR067C, L2189) |
Protein name |
Pentatricopeptide repeat-containing protein PET309, mitochondrial |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YLR067C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P32522
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P32522-F1 | Predicted | AlphaFoldDB |
12 variants for P32522
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s12-270477 | 79 | A>T | No | SGRP | |
| s12-270393 | 107 | K>E | No | SGRP | |
| s12-269840 | 291 | M>R | No | SGRP | |
| s12-269474 | 413 | T>K | No | SGRP | |
| s12-269216 | 499 | I>S | No | SGRP | |
| s12-269207 | 502 | N>S | No | SGRP | |
| s12-269054 | 553 | T>N | No | SGRP | |
| s12-268560 | 718 | I>V | No | SGRP | |
| s12-268301 | 804 | K>R | No | SGRP | |
| s12-268257 | 819 | A>T | No | SGRP | |
| s12-267996 | 906 | D>N | No | SGRP | |
| s12-267881 | 944 | M>K | No | SGRP |
No associated diseases with P32522
1 regional properties for P32522
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pentatricopeptide repeat | 345 - 379 | IPR002885 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| extrinsic component of mitochondrial inner membrane | The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| translation regulator activity | Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. |
| tRNA binding | Binding to a transfer RNA. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial cytochrome c oxidase assembly | The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. |
| positive regulation of mitochondrial translational initiation | Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. |
| tRNA 3'-end processing | The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKRCAPAVLR | NYNYKKGIWS | TGVPDHIRKL | LRDKSTSPLC | SQDERNLVSY | FMARGSVPLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SVGSGLTKKA | TTSITSNSAT | TTFERQYLIK | YLYRHQAYGN | VIKIAQKFLY | TTIGSQRLLK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QDASLPELKK | FLLSLLILQR | GIQLDQAISD | IIQRFLLTQK | TMVIDLINSI | FSRMVIMNMH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EEAVYKWVKW | MKLVNGHCEF | TNYMENKIVL | RNFLSFMRQS | NVRPDYLSYL | KAIQLTQGPA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IASQFATTLL | FLLTYIRKFS | SAEAVWNYKC | EHNLPIVSSD | LTCILKTYCH | MQKFNLVSST |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YWKYPDAQHD | QNQFDYLLVA | HSRLHNWDAL | QQQFNALFGI | GKLPSIQHYG | ILMYTMARIG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ELDSVNKLYT | QLLRRGMIPT | YAVLQSLLYA | HYKVGDFAAC | FSHFELFKKY | DITPSTATHT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IMLKVYRGLN | DLDGAFRILK | RLSEDPSVEI | TEGHFALLIQ | MCCKTTNHLI | AQELFNLMTE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HYNIQHTGKS | ISALMDVYIE | SNRPTEAIAL | FEKHSKNLSW | RDGLISVYNK | AIKAYIGLRN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ANKCEELFDK | ITTSKLAVNS | EFYKMMIKFL | VTLNEDCETA | LSIIDQLIKH | SVIKVDATHF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EIIMEAYDKE | GYRDGIINLY | KTMSQNKVPA | NSKILYYILK | AVAKKSLQNN | EEIKETINMV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| EDIMENAANG | TLDVTYNKLH | PSVMAWPMRM | IVKHDSPQRA | LELYNRYNEL | FFKKHDWISN |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NNKFVMMRSL | LVLLAQIEQW | KDFETLFAKY | MDRIENIENL | PSSTTPNIKL | RSIFSGLFPY |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KVSQLIAMNK | IDELPLLWKK | LREKGFILDN | ISWNSAVEAL | FKDPRTLSYG | MKIVDDTLIH |
| 850 | 860 | 870 | 880 | 890 | 900 |
| GYNLIHKFRL | LTKLSEDKTQ | SSDKSWPTLK | MKEKEPNKFQ | PRLYLKSDTY | NSIMRQLDTY |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LDGIDDLKTL | EDQVRDFISN | YKYFMKDYLL | MPRSKINKWE | QIEMRHLSYF | KELRKSKRVL |
| PVSKF |