P32464

PR
Gene name
HYM1 (YKL189W)
Protein name
Protein HYM1
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YKL189W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P32464

Entry ID Method Resolution Chain Position Source
AF-P32464-F1 Predicted AlphaFoldDB

10 variants for P32464

Variant ID(s) Position Change Description Diseaes Association Provenance
s11-84841 45 D>H No SGRP
s11-84970 88 A>T No SGRP
s11-85127 140 L>S No SGRP
s11-85141 145 A>T No SGRP
s11-85280 191 A>V No SGRP
s11-85340 211 T>I No SGRP
s11-85441 245 V>I No SGRP
s11-85750 348 Q>E No SGRP
s11-85826 373 V>A No SGRP
s11-85901 398 S>* No SGRP

No associated diseases with P32464

No regional properties for P32464

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P32464

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cellular bud A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
incipient cellular bud site The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
mating projection tip The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
mitotic spindle pole body The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.

1 GO annotations of molecular function

Name Definition
protein serine/threonine kinase activator activity Binds to and increases the activity of a protein serine/threonine kinase.

4 GO annotations of biological process

Name Definition
budding cell apical bud growth Growth at the tip of a bud, in a cell that reproduces by budding.
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
septum digestion after cytokinesis The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9ZQ77 At2g03410 MO25-like protein At2g03410 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV QEECTKYLIG
70 80 90 100 110 120
TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD LEFEARRECM LIFSICLGYS
130 140 150 160 170 180
KDNKFVTVDY LVSQPKTISL MLRTAEVALQ QKGCQDIFLT VGNMIIECIK YEQLCRIILK
190 200 210 220 230 240
DPQLWKFFEF AKLGNFEIST ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA
250 260 270 280 290 300
HGSYVTKRQS TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK
310 320 330 340 350 360
VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI DSLPRIISST
370 380 390
TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR