P32463

PR
Gene name
ACP1 (YKL192C)
Protein name
Acyl carrier protein, mitochondrial
Names
ACP, NADH-ubiquinone oxidoreductase 9.6 kDa subunit
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YKL192C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P32463

Entry ID Method Resolution Chain Position Source
AF-P32463-F1 Predicted AlphaFoldDB

3 variants for P32463

Variant ID(s) Position Change Description Diseaes Association Provenance
s11-80496 16 A>V No SGRP
s11-80358 62 N>S No SGRP
s11-80205 113 E>G No SGRP

No associated diseases with P32463

2 regional properties for P32463

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 276 - 289 IPR004838
domain Aminotransferase, class I/classII 51 - 431 IPR004839

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
iron-sulfur cluster assembly complex A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.
mitochondrial iron-sulfur cluster assembly complex A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

2 GO annotations of molecular function

Name Definition
acyl binding Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
acyl carrier activity Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.

2 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
lipoate biosynthetic process The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFRSVCRISS RVAPSAYRTI MGRSVMSNTI LAQRFYSANL SKDQVSQRVI DVIKAFDKNS
70 80 90 100 110 120
PNIANKQISS DTQFHKDLGL DSLDTVELLV AIEEEFDIEI PDKVADELRS VGETVDYIAS
NPDAN