| adult locomotory behavior |
Locomotory behavior in a fully developed and mature organism. |
| anatomical structure formation involved in morphogenesis |
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. |
| anatomical structure morphogenesis |
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. |
| anterior/posterior pattern specification |
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
| cell development |
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. |
| cell differentiation |
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| cell differentiation in hindbrain |
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
| cell fate specification |
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. |
| cellular response to cadmium ion |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. |
| chromatin organization |
The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| connective tissue development |
The progression of a connective tissue over time, from its formation to the mature structure. |
| dopaminergic neuron differentiation |
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. |
| dorsal/ventral neural tube patterning |
The process in which the neural tube is regionalized in the dorsoventral axis. |
| dorsal/ventral pattern formation |
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. |
| ectoderm formation |
The formation of ectoderm during gastrulation. |
| endocrine pancreas development |
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. |
| epithelial tube branching involved in lung morphogenesis |
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. |
| gene expression |
The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes. |
| in utero embryonic development |
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. |
| lung development |
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. |
| lung epithelial cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. |
| mesendoderm development |
The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues. |
| negative regulation of detection of glucose |
Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose. |
| negative regulation of DNA-binding transcription factor activity |
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. |
| negative regulation of epithelial to mesenchymal transition |
Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
| negative regulation of glucokinase activity |
Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. |
| negative regulation of neuron differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. |
| negative regulation of transcription from RNA polymerase II promoter by glucose |
Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter. |
| neuron differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a neuron. |
| neuron fate specification |
The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. |
| Notch signaling pathway |
The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| pattern specification process |
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. |
| positive regulation of DNA-templated transcription |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of dopaminergic neuron differentiation |
Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. |
| positive regulation of embryonic development |
Any process that activates or increases the frequency, rate or extent of embryonic development. |
| positive regulation of gastrulation |
Any process that activates or increases the frequency, rate or extent of gastrulation. |
| positive regulation of neuron differentiation |
Any process that activates or increases the frequency, rate or extent of neuron differentiation. |
| positive regulation of smoothened signaling pathway |
Any process that activates or increases the frequency, rate or extent of smoothened signaling. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| positive regulation of transcription by RNA polymerase III |
Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III. |
| positive regulation of transcription from RNA polymerase II promoter by glucose |
Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter. |
| primitive streak formation |
The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. |
| regulation of blood coagulation |
Any process that modulates the frequency, rate or extent of blood coagulation. |
| regulation of DNA-templated transcription |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of gene expression |
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| regulation of insulin secretion involved in cellular response to glucose stimulus |
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. |
| regulation of lipid metabolic process |
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. |
| regulation of steroid metabolic process |
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. |
| regulation of transcription by RNA polymerase II |
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| response to insulin |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. |
| signal transduction involved in regulation of gene expression |
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. |
| smoothened signaling pathway |
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. |
| somite rostral/caudal axis specification |
The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary. |
| transcription by RNA polymerase II |
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). |
